Understanding how different plant-based proteins are digested in people with ileostomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study aims to investigate the digestibility of various plant-based proteins in adults aged 18 to 75 who have an ileostomy. Participants will consume five different protein meals on separate days, including high and low bioavailable oat and pea proteins, as well as a protein-free meal. The study will analyze how well these proteins are digested in the small intestine and what metabolites are produced, with the goal of comparing in vivo results to existing in vitro models. The findings could provide insights into optimizing dietary protein sources for individuals with ileostomies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 18 - 75 years
* Body mass index: 18.5 - 30 kg/m2
* (double-loop) Ileostomy with an intact small bowel
* Signed informed consent

Exclusion Criteria:

* Pregnancy or breastfeeding
* Ileostomy \< 3 months before the study
* Any clinically significant present or past disease/condition other than colon cancer which in the investigator's opinion could interfere with the results of the trial
* Any clinically significant present or past medication which in the investigator's opinion could interfere with the results of the trial

Where it's running

• Örebro University
  Örebro, Sweden Recruiting

Study contacts

• Study coordinator: Robert Brummer, PhD
• Email: robert.brummer@oru.se
• Phone: 004619303731

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Stoma education and its effects on patients

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• Magnesium status in people with IBD, ileostomy, or bile acid diarrhea

  This will test different ways to check magnesium in adults with Crohn's disease, ulcerative colitis, ileostomies, or bile acid diarrhea to see which method best finds deficiency.

  Recruiting University of Aarhus · Aarhus N · NCT07338565

• Drug absorption in people with an ostomy

  This study will test whether commonly used psychotropic medicines and newer oral blood thinners reach expected levels in adults who have an ileostomy or colostomy.

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• Preventing dehydration and readmission after elective ileostomy

  See if clinicians calculate the DRIP score and apply its recommended steps for adults having an elective ileostomy to reduce dehydration and readmission at several Italian centers.

  Recruiting at 7 sites Multidisciplinary Italian Study group for STOmas (MISSTO) · Legnano, Italy and 6 other locations · NCT06824623

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.