Magnesium status in people with IBD, ileostomy, or bile acid diarrhea
Official title: Magnesium Status in Patients With Gastrointestinal Disease
Run by University of Aarhus · NCT07338565 · Data updated 2026-11-12
This will test different ways to check magnesium in adults with Crohn's disease, ulcerative colitis, ileostomies, or bile acid diarrhea to see which method best finds deficiency.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | University of Aarhus Academic / other |
| Locations | 1 site (Aarhus N) |
| Status | Recruiting |
| Started | November 3, 2025 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2027 |
| Registry record updated | January 14, 2026 |
| Trial ID | NCT07338565 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older who understand Danish and have a diagnosis of Crohn's disease, ulcerative colitis, an ileostomy, or bile acid diarrhoea (or healthy volunteers for the control group) are the intended participants.
✕Probably not a fit
People who are pregnant or breastfeeding, under 18, unable to understand Danish, or who have used oral magnesium supplements recently are not eligible and are unlikely to gain direct benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This cross-sectional study enrolls adults with inflammatory bowel disease, ileostomy, or bile acid diarrhoea and a group of healthy controls to compare multiple biochemical and functional magnesium markers. Participants will attend up to four visits during which blood, cellular, and possibly urine tests and functional assessments will be performed to compare plasma magnesium with intracellular and other measures. The aim is to identify which tests most accurately and practically reflect whole-body magnesium status in people with chronic intestinal disorders. Results are intended to inform a more sensitive screening approach for magnesium deficiency in clinical practice.
Why it matters
Potential benefit: If successful, the work could lead to earlier and more accurate detection of magnesium deficiency, enabling targeted treatment and improved symptoms and quality of life for affected patients.
How similar studies have gone: Prior work has shown routine plasma magnesium often misses deficiency and smaller studies suggest intracellular or functional tests can be more sensitive, but comprehensive comparisons specifically in gastrointestinal patient groups remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Age 18 or older, mentally competent, and able to understand Danish. Group 1: \- Diagnosed with IBD (DK50X, Crohn's disease, or DK51X, ulcerative colitis), ileostomy (DZ932) or bile acid diarrhoea (DSK908B) (Se-HCAT scintigraphy showing residual activity \<10%). Group 2: \- Healthy individuals. Exclusion Criteria: * Pregnant or breastfeeding. * Use of oral magnesium supplements for more than 2 weeks before inclusion.
Where it's running
-
Department of Hepatology and Gastroenterology, Aarhus University Hospital
Aarhus N, Denmark Recruiting
Study contacts
- Study coordinator: Mathias Redsted
- Email: matred@clin.au.dk
- Phone: +4530519619
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.