Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding how aging cells affect patients with circulatory shock

Official title: Impact of Endothelial and Leukocyte Senescence in Circulatory Shock States

Run by University Hospital, Strasbourg, France · NCT03559569 · Data updated 2026-11-12

This study looks at how aging cells in the blood might affect patients who have gone through circulatory shock, to see if they contribute to complications like infections and heart problems after recovery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment520 (estimated)
SponsorUniversity Hospital, Strasbourg, France
Academic / other
Locations1 site (Strasbourg)
StatusRecruiting
StartedJanuary 7, 2019
Main results expectedFebruary 2028
Study endsMarch 2028
Registry record updatedMarch 10, 2025
Trial IDNCT03559569 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients experiencing circulatory shock who have health care insurance.

Probably not a fit

Patients who refuse to participate in clinical research, pregnant or breastfeeding women, and those under a protective order may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the role of endothelial and leukocyte senescence in patients experiencing circulatory shock, a critical condition characterized by acute organ dysfunction. The researchers aim to determine how premature aging of these cells contributes to the development of secondary infections and cardiovascular diseases in survivors of circulatory shock. By analyzing biological samples, the study seeks to enhance understanding of the underlying mechanisms that lead to these complications, potentially informing new management strategies for affected patients.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and management strategies for cardiovascular diseases and infections in patients recovering from circulatory shock.

How similar studies have gone: While the specific approach of this study may be novel, related research has indicated that understanding cellular senescence can provide insights into complications following critical illnesses.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Circulatory shock
* patient with health care insurance

Exclusion criteria:

* Patients' refusal to participate in clinical research
* Pregnant woman
* Breastfeeding woman
* A patient with a protective order

Where it's running

  • Hôpitaux Universitaires de Strasbourg - Service de Réanimation médicale du NHC
    Strasbourg, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.