Understanding Heart Failure With Preserved Ejection Fraction
Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)
This study looks at people with heart failure that has preserved ejection fraction to understand what causes it and find better tests and treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Manchester University NHS Foundation Trust Government |
| Locations | 1 site (Manchester) |
| Trial ID | NCT05383287 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on heart failure with preserved ejection fraction (HFpEF), a condition where the heart struggles to pump blood effectively. It aims to identify the underlying causes of HFpEF, explore new tests and treatments, and assess the life expectancy of affected individuals. By collecting data from patients attending a specialized HFpEF clinic, the study seeks to characterize different phenotypes of HFpEF and their clinical outcomes, ultimately guiding future research and personalized care strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults attending the HFpEF clinic at Manchester University NHS Foundation Trust.
Not a fit: Patients under 18 years old, those who are imprisoned, or those unable to provide informed consent in English may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and targeted treatments for patients with HFpEF.
How similar studies have performed: While HFpEF has been a challenging area with limited treatment success, the approach of characterizing patient phenotypes is gaining traction and has shown promise in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients attending the HFpEF clinic at MFT. Exclusion Criteria: * Age \< 18 years * Imprisonment * Inability to provide full written or verbal informed consent in English
Where this trial is running
Manchester
- Manchester University NHS Foundation trust — Manchester, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Chris Miller, MBChB, MRCP — Manchester University NHS FT
- Study coordinator: Fardad Soltani, MBChB, MRCP
- Email: fardad.soltani@mft.nhs.uk
- Phone: 0161 291 3223
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.