Understanding heart changes in patients with heart failure
Investigating Myocardial Remodelling in the Failing Human Heart
This study looks at how the hearts of people with heart failure change over time using advanced imaging to help us better understand the condition and improve treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo, Oslo) |
| Trial ID | NCT05303896 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the features and mechanisms of myocardial remodeling in patients with heart failure. By utilizing advanced imaging techniques such as MRI and PET, the study will assess the structure and function of failing hearts, providing insights into the cellular and extracellular changes that occur. The findings could enhance our understanding of heart failure and inform future therapeutic strategies.
Who should consider this trial
Good fit: Ideal candidates are patients eligible for heart transplantation who can provide informed consent.
Not a fit: Patients under the age of 18 will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved patient care and treatment options for individuals with heart failure.
How similar studies have performed: While there have been studies on myocardial remodeling, this specific approach using comprehensive imaging in heart failure patients is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Eligible for heart transplantation * Willingness to participate in the present study and ability to understand and sign the written informed consent Exclusion Criteria: * Patients under the age of 18.
Where this trial is running
Oslo, Oslo
- Oslo University Hospital — Oslo, Oslo, Norway (Recruiting)
Study contacts
- Principal investigator: Ivar Sjaastad, MD, PhD — University of Oslo, Oslo University Hospital
- Study coordinator: Henrik Dukefoss, MD
- Email: h.b.dukefoss@studmed.uio.no
- Phone: 95433188
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.