Understanding heart changes in patients with heart failure
Official title: Investigating Myocardial Remodelling in the Failing Human Heart
Run by Oslo University Hospital · NCT05303896 · Data updated 2026-11-12
This study looks at how the hearts of people with heart failure change over time using advanced imaging to help us better understand the condition and improve treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo, Oslo) |
| Status | Recruiting |
| Started | May 30, 2022 |
| Main results expected | July 2030 |
| Study ends | July 2030 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT05303896 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients eligible for heart transplantation who can provide informed consent.
✕Probably not a fit
Patients under the age of 18 will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the features and mechanisms of myocardial remodeling in patients with heart failure. By utilizing advanced imaging techniques such as MRI and PET, the study will assess the structure and function of failing hearts, providing insights into the cellular and extracellular changes that occur. The findings could enhance our understanding of heart failure and inform future therapeutic strategies.
Why it matters
Potential benefit: If successful, this study could lead to improved patient care and treatment options for individuals with heart failure.
How similar studies have gone: While there have been studies on myocardial remodeling, this specific approach using comprehensive imaging in heart failure patients is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Eligible for heart transplantation * Willingness to participate in the present study and ability to understand and sign the written informed consent Exclusion Criteria: * Patients under the age of 18.
Where it's running
-
Oslo University Hospital
Oslo, Oslo, Norway Recruiting
Study contacts
- Principal investigator: Ivar Sjaastad, MD, PhD — University of Oslo, Oslo University Hospital
- Study coordinator: Henrik Dukefoss, MD
- Email: h.b.dukefoss@studmed.uio.no
- Phone: 95433188
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.