Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Understanding heart changes in patients with heart failure

Official title: Investigating Myocardial Remodelling in the Failing Human Heart

Run by Oslo University Hospital · NCT05303896 · Data updated 2026-11-12

This study looks at how the hearts of people with heart failure change over time using advanced imaging to help us better understand the condition and improve treatments.

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment200 (estimated)
SponsorOslo University Hospital
Academic / other
Locations1 site (Oslo, Oslo)
StatusRecruiting
StartedMay 30, 2022
Main results expectedJuly 2030
Study endsJuly 2030
Registry record updatedOctober 16, 2026
Trial IDNCT05303896 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients eligible for heart transplantation who can provide informed consent.

Probably not a fit

Patients under the age of 18 will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the features and mechanisms of myocardial remodeling in patients with heart failure. By utilizing advanced imaging techniques such as MRI and PET, the study will assess the structure and function of failing hearts, providing insights into the cellular and extracellular changes that occur. The findings could enhance our understanding of heart failure and inform future therapeutic strategies.

Why it matters

Potential benefit: If successful, this study could lead to improved patient care and treatment options for individuals with heart failure.

How similar studies have gone: While there have been studies on myocardial remodeling, this specific approach using comprehensive imaging in heart failure patients is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible for heart transplantation
* Willingness to participate in the present study and ability to understand and sign the written informed consent

Exclusion Criteria:

* Patients under the age of 18.

Where it's running

  • Oslo University Hospital
    Oslo, Oslo, Norway
    Recruiting

Study contacts

  • Principal investigator: Ivar Sjaastad, MD, PhD — University of Oslo, Oslo University Hospital
  • Study coordinator: Henrik Dukefoss, MD
  • Email: h.b.dukefoss@studmed.uio.no
  • Phone: 95433188

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.