Understanding head and neck cancer through detailed cellular analysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the high-resolution single-cell profiling of cancer-associated fibroblasts in patients with HPV-positive oropharyngeal squamous cell carcinoma and their metastatic lymph nodes. Participants will undergo photography, blood sample collection, and tissue collection, while their medical records will be reviewed to gather comprehensive data on the disease. The aim is to evaluate the cellular and biomarker characteristics associated with the aggressive behavior of head and neck cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis/disease status: New diagnosis of head and neck cancer
* Allowable type and amount of prior therapy: No prior treatment
* Age ≥ 18 years.
* Ability to understand and the willingness to sign a written informed consent.

Exclusion Criteria:

* Patients who have had treatment of head and neck cancer

Where it's running

• USC / Norris Comprehensive Cancer Center
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Albert Y Han, MD — University of Southern California
• Study coordinator: Sandy Tran, MS
• Email: sandy.tran@med.usc.edu
• Phone: 323-865-0451

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.