Understanding frailty in patients with vascular diseases undergoing surgery

Vascular Frailty - An Observational Cohort Study

Imperial College London · NCT03668821

This study looks at how frailty affects patients with vascular diseases who are having surgery to see if it impacts their recovery and quality of life.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorImperial College London (other)
Locations2 sites (London and 1 other locations)
Trial IDNCT03668821 on ClinicalTrials.gov

What this trial studies

This observational cohort study investigates the prevalence of frailty among patients undergoing vascular surgical procedures, such as aortic aneurysm repair and carotid artery surgery. It aims to assess how frailty and pre-operative activity levels impact surgical outcomes, morbidity, mortality, and quality of life. By utilizing questionnaires, the study will quantify frailty levels and explore their correlation with surgical results, ultimately guiding future interventions to improve patient outcomes. The findings are expected to lay the groundwork for future studies focused on enhancing frailty management in this patient population.

Who should consider this trial

Good fit: Ideal candidates include patients scheduled for aortic aneurysm repair, carotid artery surgery, or lower limb revascularization who can provide informed consent.

Not a fit: Patients under 18 years of age or those unable to provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for patients with vascular diseases.

How similar studies have performed: Other studies have indicated that frailty significantly impacts surgical outcomes, suggesting that this approach is both relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. All patients attending for aortic aneurysm repair, carotid artery surgery and lower limb revascularisation under the care of the Vascular Surgery team
2. Willing and able to give informed written consent

Exclusion Criteria:

1. Those unable to give informed written consent
2. Those \<18 years of age
3. In the opinion of the investigator unable or unwilling to comply with the requirements of the study

Where this trial is running

London and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vascular Diseases, Carotid Artery Diseases, Aneurysmal Disease, Peripheral Artery Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.