Understanding COVID-19 in kidney transplant recipients in Brazil
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Infection (COVID-19) in Kidney Transplant Recipients: a Brazilian Multicenter Study
Hospital do Rim e Hipertensão · NCT04494776
This study looks at how COVID-19 affects kidney transplant patients in Brazil to see what challenges they face and what happens to them after getting the virus.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | Hospital do Rim e Hipertensão (other) |
| Locations | 1 site (São Paulo, Aão Paulo) |
| Trial ID | NCT04494776 on ClinicalTrials.gov |
What this trial studies
This observational study aims to characterize the demographics, clinical conditions, and outcomes of COVID-19 in kidney transplant recipients across multiple centers in Brazil. It focuses on patients who have tested positive for SARS-CoV-2 and examines factors such as the need for mechanical ventilation, dialysis, and ICU admission. The study will also assess outcomes like death and graft loss within three months after infection. By gathering this data, the research seeks to provide insights into the atypical presentation and progression of COVID-19 in immunosuppressed individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are kidney transplant recipients of any age who have tested positive for COVID-19.
Not a fit: Patients who are not kidney transplant recipients or those who have not tested positive for COVID-19 will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve understanding of COVID-19 outcomes in kidney transplant recipients, leading to better management strategies.
How similar studies have performed: While there is limited information specifically on kidney transplant recipients, preliminary evidence suggests worse outcomes in immunosuppressed patients, indicating a need for this type of research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Kidney transplant recipients, which may be multi-organ recipients, transplanted in any follow-up period; 2. Positive diagnostic test for COVID-19 (detection of viral load, test for detection of antigens or tests for detection of antibodies); 3. Outpatient or hospital management; 4. Adults and children. Exclusion Criteria: \-
Where this trial is running
São Paulo, Aão Paulo
- Hospital do Rim — São Paulo, Aão Paulo, Brazil (RECRUITING)
Study contacts
- Study coordinator: Helio Tedesco
- Email: heliotedesco@medfarm.com.br
- Phone: +55 11 5087-8113
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: SARS-CoV-2 Infection, Kidney Transplant Infection, Kidney Transplant