Clinical trial Recruiting at 1 site Observational

Understanding COVID-19 in kidney transplant recipients in Brazil

Official title: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Infection (COVID-19) in Kidney Transplant Recipients: a Brazilian Multicenter Study

Run by Hospital do Rim e Hipertensão · NCT04494776 · Data updated 2026-11-12

This study looks at how COVID-19 affects kidney transplant patients in Brazil to see what challenges they face and what happens to them after getting the virus.

More SARS CoV 2 Infection trials

Quick facts

Study typeObservational
SexAll
Enrollment500 (estimated)
SponsorHospital do Rim e Hipertensão
Academic / other
Locations1 site (São Paulo, Aão Paulo)
StatusRecruiting
StartedMay 21, 2020
Main results expectedDecember 3, 2022
Study endsApril 2, 2025
Registry record updatedNovember 8, 2024
Trial IDNCT04494776 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are kidney transplant recipients of any age who have tested positive for COVID-19.

Probably not a fit

Patients who are not kidney transplant recipients or those who have not tested positive for COVID-19 will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize the demographics, clinical conditions, and outcomes of COVID-19 in kidney transplant recipients across multiple centers in Brazil. It focuses on patients who have tested positive for SARS-CoV-2 and examines factors such as the need for mechanical ventilation, dialysis, and ICU admission. The study will also assess outcomes like death and graft loss within three months after infection. By gathering this data, the research seeks to provide insights into the atypical presentation and progression of COVID-19 in immunosuppressed individuals.

Why it matters

Potential benefit: If successful, this study could improve understanding of COVID-19 outcomes in kidney transplant recipients, leading to better management strategies.

How similar studies have gone: While there is limited information specifically on kidney transplant recipients, preliminary evidence suggests worse outcomes in immunosuppressed patients, indicating a need for this type of research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Kidney transplant recipients, which may be multi-organ recipients, transplanted in any follow-up period;
2. Positive diagnostic test for COVID-19 (detection of viral load, test for detection of antigens or tests for detection of antibodies);
3. Outpatient or hospital management;
4. Adults and children.

Exclusion Criteria:

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Where it's running

  • Hospital do Rim
    São Paulo, Aão Paulo, Brazil
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.