Understanding COVID-19 in kidney transplant recipients in Brazil
Official title: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Infection (COVID-19) in Kidney Transplant Recipients: a Brazilian Multicenter Study
Run by Hospital do Rim e Hipertensão · NCT04494776 · Data updated 2026-11-12
This study looks at how COVID-19 affects kidney transplant patients in Brazil to see what challenges they face and what happens to them after getting the virus.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Hospital do Rim e Hipertensão Academic / other |
| Locations | 1 site (São Paulo, Aão Paulo) |
| Status | Recruiting |
| Started | May 21, 2020 |
| Main results expected | December 3, 2022 |
| Study ends | April 2, 2025 |
| Registry record updated | November 8, 2024 |
| Trial ID | NCT04494776 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are kidney transplant recipients of any age who have tested positive for COVID-19.
✕Probably not a fit
Patients who are not kidney transplant recipients or those who have not tested positive for COVID-19 will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to characterize the demographics, clinical conditions, and outcomes of COVID-19 in kidney transplant recipients across multiple centers in Brazil. It focuses on patients who have tested positive for SARS-CoV-2 and examines factors such as the need for mechanical ventilation, dialysis, and ICU admission. The study will also assess outcomes like death and graft loss within three months after infection. By gathering this data, the research seeks to provide insights into the atypical presentation and progression of COVID-19 in immunosuppressed individuals.
Why it matters
Potential benefit: If successful, this study could improve understanding of COVID-19 outcomes in kidney transplant recipients, leading to better management strategies.
How similar studies have gone: While there is limited information specifically on kidney transplant recipients, preliminary evidence suggests worse outcomes in immunosuppressed patients, indicating a need for this type of research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Kidney transplant recipients, which may be multi-organ recipients, transplanted in any follow-up period; 2. Positive diagnostic test for COVID-19 (detection of viral load, test for detection of antigens or tests for detection of antibodies); 3. Outpatient or hospital management; 4. Adults and children. Exclusion Criteria: \-
Where it's running
-
Hospital do Rim
São Paulo, Aão Paulo, Brazil Recruiting
Study contacts
- Study coordinator: Helio Tedesco
- Email: heliotedesco@medfarm.com.br
- Phone: +55 11 5087-8113
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.