Understanding COVID-19 in children with cancer

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

Observational St. Jude Children's Research Hospital · NCT04371315

This study is trying to understand how COVID-19 affects children with cancer by collecting samples and looking at their health outcomes and risk factors.

Quick facts

Study typeObservational
Enrollment400 (estimated)
AgesN/A to 24 Years
SexAll
SponsorSt. Jude Children's Research Hospital Academic / other
Locations1 site (Memphis, Tennessee)
Trial IDNCT04371315 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather respiratory and blood samples from children under 24 years old who have been diagnosed with COVID-19. The primary focus is to determine the clinical characteristics and outcomes of COVID-19 in this population, as well as to identify risk factors associated with the disease. By analyzing these samples, researchers hope to gain insights into how the virus spreads and affects children, particularly those with underlying health conditions like cancer. Follow-up samples will be collected based on standard care procedures to monitor the disease progression and immune response.

Who should consider this trial

Good fit: Ideal candidates for this study are children under 24 years old with laboratory-confirmed COVID-19 who are patients at St. Jude Children's Research Hospital.

Not a fit: Patients who do not have COVID-19 or are over the age of 24 will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of COVID-19 in children, leading to improved detection and treatment strategies.

How similar studies have performed: Other studies have explored COVID-19 in pediatric populations, but this specific focus on children with cancer is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Patient Participant Inclusion Criteria:

* Less than 24 years old at the time of enrollment on study.
* St. Jude patients with laboratory confirmed Covid-19.

Exclusion Criteria:

* NA

Where this trial is running

Memphis, Tennessee

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Corona Virus InfectionPediatric CancerAdult ChildrenCancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.