Understanding cancer-related fatigue in survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot study aims to explore how cancer-related fatigue impacts survivors and how it is communicated with healthcare providers. Participants will include adults who have completed cancer treatment over six months ago and are experiencing fatigue. The study will involve a six-minute walk test, surveys, and virtual interviews with both cancer survivors and clinicians to gather qualitative and quantitative data. The findings will be used to create an educational visual aid to facilitate discussions about managing cancer-related fatigue.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ability to comply with study procedures for the duration of the study

Survivors:

* Written informed consent and HIPAA authorization for release of personal information
* Ability to read/write, understand and converse in English without the need for an interpreter
* Men and women aged ≥ 18 years at the time of consent
* History of at least one visit for the purpose of monitoring long term care post curative treatment at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC
* Completed curative treatment \> 6 months ago for any cancer type, with no detectable evidence of cancer
* Self-reported tiredness, exhaustion, or weakness (i.e. fatigue) score of ≥ 4 on the Numerical Rating Scale
* Adjuvant endocrine therapy to reduce the risk of cancer returning is acceptable (i.e. tamoxifen or aromatase inhibitors).

Clinicians:

\- Currently see oncology patients (any cancer type) for survivorship care at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC

Exclusion Criteria:

Survivors:

* Continuing maintenance therapy or other cancer-related treatment (i.e. immunotherapy)
* History of or current untreated Major Depressive Disorders or untreated severe depression
* Hemoglobin \<11g/dL at last CBC SOC lab collection
* History/diagnosis of dementia
* Factors or conditions, for which participation may (1) not be in the best interest or (2) interfere with study assessment results (e.g. medical comorbidities, primary brain tumor/metastases)
* No access to internet/Wi-Fi

Clinicians:

\- None

Where it's running

• Levine Childrens Hospital Pediatric Cancer and Blood Disorders
  Charlotte, North Carolina, United States Recruiting
• Levine Cancer Institute
  Charlotte, North Carolina, United States Recruiting
• Wake Forest Baptist Comprehensive Cancer Center
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Dori Beeler, PhD — Atrium Health Wake Forest Baptist Comprehensive Cancer Center
• Study coordinator: Megan Lattanze
• Email: Megan.Lattanze@advocatehealth.org
• Phone: (980) 442-4239

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.