Ultrasound-guided Quadro-Iliac Plane block for pain after total hip replacement
Official title: Effectiveness of Ultrasound-Guided Quadro-Iliac Plane Block for Pain Management After Total Hip Arthroplasty: A Prospective Randomized Study
Run by Bursa City Hospital · NCT07410000 · Data updated 2026-11-12
This trial will test whether an ultrasound-guided Quadro-Iliac Plane (QIP) block reduces opioid use and pain in adults having elective primary total hip arthroplasty.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Bursa City Hospital Government |
| Locations | 1 site (Bursa) |
| Status | Recruiting |
| Started | March 16, 2026 |
| Main results expected | November 9, 2026 |
| Study ends | March 15, 2027 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07410000 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 years with ASA physical status I–III scheduled for elective primary total hip arthroplasty who are not chronic opioid users and have no contraindications to regional anesthesia are ideal candidates.
✕Probably not a fit
Patients with chronic opioid use, prior hip surgery, coagulopathy, infection at the injection site, severe cardiac/hepatic/renal disease, pregnancy or breastfeeding, or severe neurologic/psychiatric disorders are excluded and unlikely to receive benefit from enrollment.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, randomized, double-blind trial comparing an ultrasound-guided Quadro-Iliac Plane (QIP) block to a sham saline injection in adults aged 18–80 with ASA I–III undergoing elective primary total hip arthroplasty. Participants receive either 40 mL of 0.25% local anesthetic with epinephrine delivered to the QIP plane or 40 mL of saline using the same technique, with blinding of patients and outcome assessors. The primary outcome is total opioid consumption during the first 24 postoperative hours, and secondary outcomes include motor block, dermatomal sensory assessment, pain scores, rescue analgesic use, QoR-15 recovery scores, and opioid-related side effects. Patients with contraindications to regional anesthesia or chronic opioid use are excluded to ensure safety and clear interpretation of analgesic effects.
Why it matters
Potential benefit: If successful, the QIP block could reduce opioid requirements and improve postoperative pain control and recovery after hip replacement.
How similar studies have gone: Related fascial plane blocks such as fascia iliaca and quadratus lumborum blocks have often shown reductions in postoperative pain and opioid use, but the QIP block is recently described and has limited prior clinical data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) classification I-III * Age between 18 and 80 years * Patients scheduled for elective primary total hip arthroplasty Exclusion Criteria: * Refusal to participate in the study * Allergy to local anesthetics or opioids * Known or suspected coagulopathy * Infection at the injection site * History of previous hip surgery * Severe cardiovascular disease * Liver or kidney failure * Pregnancy, suspected pregnancy, or breastfeeding * Severe neurological or psychiatric disorder * Chronic opioid use
Where it's running
-
Bursa City Hospital
Bursa, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mursel Ekinci, Assoc prof,MD
- Email: drmurselekinci@gmail.com
- Phone: +905067137596
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.