Ultrasound-guided Quadro-Iliac Plane Block for pain after lumbar spine surgery
Evaluation of the Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia in Patients Undergoing Lumbar Spinal Surgery
This project will test whether adding an ultrasound-guided Quadro-Iliac Plane Block to routine pain care helps adults having elective lumbar spine surgery have less pain and use fewer opioids.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Fatih Sultan Mehmet Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Istanbul) |
| Trial ID | NCT07326774 on ClinicalTrials.gov |
What this trial studies
This is a single-center, prospective observational cohort of adults undergoing elective posterior lumbar spinal instrumentation under general anesthesia. All patients receive standardized general anesthesia and postoperative tramadol patient-controlled analgesia, and the choice to perform bilateral ultrasound-guided Quadro-Iliac Plane Block (QIPB) or local anesthetic incision infiltration is made by the attending anesthesiologist as part of routine care. Pain scores at rest and on movement and opioid consumption will be recorded in the post-anesthesia care unit and at 1, 6, 12, and 24 hours after surgery to compare outcomes between cohorts. No interventions or random assignments are performed by the investigators, and eligibility is limited to ASA I-III adults aged 18-65 with BMI under 35 kg/m² who can provide informed consent.
Who should consider this trial
Good fit: Adults aged 18–65 scheduled for elective posterior lumbar spinal instrumentation under general anesthesia with ASA physical status I–III, BMI <35 kg/m², able to consent and communicate in Turkish are eligible.
Not a fit: Patients with local infection or hematoma at the block site, coagulopathy, prior surgery at the block site, severe organ failure, chronic opioid use, or allergy to local anesthetics are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, using QIPB could improve postoperative pain control and reduce opioid consumption and related side effects after lumbar spine surgery.
How similar studies have performed: Other regional and fascial plane blocks have shown pain and opioid-sparing benefits in spine and abdominal surgery, but QIPB itself is a newer technique with limited published outcome data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 65 years * American Society of Anesthesiologists (ASA) physical status I-III * Body mass index (BMI) \<35 kg/m² * Scheduled for elective posterior lumbar spinal instrumentation surgery under general anesthesia Exclusion Criteria: * Refusal to participate in the study * Emergency surgery * Local infection or hematoma at the block application site * Previous surgery at the block application site * Presence of coagulopathy * Known allergy or toxicity to local anesthetics * History of hematological, renal, or hepatic disease, or advanced respiratory or cardiac failure * Chronic analgesic use, chronic alcohol consumption, or substance abuse * Inability to speak Turkish or presence of language/communication barriers
Where this trial is running
Istanbul, Istanbul
- Fatih Sultan Mehmet Training and Research Hospital — Istanbul, Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Oznur Demiroluk, Assoc. Prof. — Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye
- Study coordinator: Elif Acar Deger, Dr.
- Email: drelifacardeger@gmail.com
- Phone: +905069435510
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.