Ultrasound-guided blocks for kids' abdominal surgery pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In children aged 2 to 7 undergoing elective open lower abdominal surgery, the study compares two ultrasound-guided regional blocks given after anesthesia: anterior quadratus lumborum block versus bilateral erector spinae plane block at T10–T12, with bupivacaine 0.25% (0.5 mL/kg per side) during the first 24 hours postoperatively. The trial is interventional and uses bilateral blocks to assess analgesic efficacy. Outcomes focus on postoperative pain control and analgesic needs within the first day after surgery. Participants are limited to ASA I–II children weighing 10–25 kg and undergoing specific open lower abdominal procedures. The study is conducted at Menoufia University in Alexandria, led by a single sponsor with no listed collaborators.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 2 to 7 years.
* ASA Physical Status Classification I or II .
* Scheduled for elective minor open lower abdominal surgery (bilateral inguinal hernia repair, orchiopexy, circumcision, bilateral hydrocele repair), pyeloplasty and ureteric reimplantation.
* Weight between 10 and 25 kg.

Exclusion Criteria

* Known allergy or hypersensitivity to local anesthetics (amide class).
* Contraindications to regional anesthesia: coagulopathy (INR \> 1.5, platelets \< 80,000/mm³), local infection at the injection site, or raised intracranial pressure.
* Pre-existing neurological, neuromuscular, or spinal disorders.
* Significant hepatic dysfunction (Child-Pugh Class B or C) or severe renal impairment (eGFR \< 30 mL/min/1.73 m²).
* Previous abdominal or retroperitoneal surgery which likely to distort fascial planes at the injection site.
* Emergency or redo surgical procedures.
* Inability to assess postoperative pain due to pre-existing developmental or cognitive impairment preventing validated pain scale use.
* Intraoperative conversion from open to laparoscopic approach (post-randomization exclusion criterion).

Where it's running

• Menoufia University
  Alexandria, Egypt Recruiting

Study contacts

• Study coordinator: Nevine Soliman, MD
• Email: mostafanevine@gmail.com
• Phone: 201128861471

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.