Ultrasound Before Corticosteroid Injection for Arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study will evaluate if therapeutic ultrasound applied prior to intra-articular corticosteroid injection improves outcomes for adults with limb arthritis. Participants must be 18 or older and have arthritis in a joint that requires injection, with exclusions including prosthetic joints, hip involvement, gout, infectious arthritis, or cellulitis at the treatment site. The study uses two interventions—therapeutic ultrasound followed by corticosteroid injection—and will monitor safety and treatment response. It is conducted at Taichung Veterans General Hospital in Taichung, Taiwan, and aims to determine if the combined approach yields better relief than injection alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Diagnosed with arthritis in the limbs.
* Inadequate response to or contraindication for oral anti-inflammatory medications.
* Assessed by a physician as requiring intra-articular corticosteroid injection.

Exclusion Criteria:

* History of joint replacement (prosthetic joint) in the affected area.
* Hip joint involvement.
* Diagnosis of gout.
* Infectious arthritis.
* Presence of cellulitis at the treatment site.

Where it's running

• Taichung Veterans General Hospital
  Taichung, Taiwan Recruiting

Study contacts

• Principal investigator: Kuo-Lung Lai, MD — Taichung Veterans General Hospital (TaichungVGH)
• Study coordinator: Kuo-Lung Lai, MD
• Email: kllaichiayi@yahoo.com.tw
• Phone: +886-4-2359-2525

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people

  This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07829497

• Ultralow-dose PET scan to detect bone activity with 18F‑NaF

  This trial tests whether a new high-sensitivity PET scan using a tiny amount of 18F‑sodium fluoride can produce clear bone images in adults with or without bone disease while cutting radiation exposure by 10–100 times.

  Recruiting Phase 2 Nuclear Imaging Institute · Englewood, New Jersey and 1 other locations · NCT07284563

• Early stratification of acute arthritis

  The project will collect clinical information and biomarker samples to try to find signs that help classify and guide treatment for adults who developed inflammatory arthritis symptoms within the past 12 weeks.

  Recruiting Diakonhjemmet Hospital · Oslo · NCT07106931

• AI-guided precision immunotherapy for rheumatoid arthritis

  This trial will see if adding the dnaJP1 peptide to hydroxychloroquine helps adults with moderately to severely active rheumatoid arthritis who have not used DMARDs or biologic treatments.

  Recruiting Phase 2 Singapore Health Services · Singapore · NCT07013110

• Biophoton therapy for chronic severe arthritis pain relief

  This study is testing if biophoton therapy can help people with chronic severe arthritis pain feel better over 12 weeks.

  Recruiting First Institute of All Medicines · Butler, Pennsylvania · NCT06915012

• Examining the effects of different exercise levels on arthritis symptoms

  This study tests how different amounts of exercise can help people with arthritis feel better over six months.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT06880653

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.