Twin Block and Low-Intensity Pulsed Ultrasound for Class II Division 1 Malocclusion in Kids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective clinical trial, 24 children aged 9–12 with skeletal Class II due to a retrognathic mandible were randomized to receive a Twin Block appliance alone or with daily low-intensity pulsed ultrasound (LIPUS) therapy. LIPUS was applied bilaterally to the temporomandibular joint region during the initial 10 days and then at least three times per week until mandibular advancement was achieved, across a nine-month treatment period. CBCT and standard orthodontic records were collected to measure dentoskeletal and TMJ parameters before and during treatment. The trial aims to determine if adding LIPUS enhances treatment-related changes compared with Twin Block alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Skeletal class II due to retrognathic mandible.
* Angle's class II Molar relationship.
* All patients involved in the study were in stages II and III based on the modified cervical vertebral maturation stages (CVMS) by Bacetti et al.5
* Proclined upper incisors
* Increased overjet \> 5 mm.
* Aligned lower arch or average inclination
* Minimal crowding of lower arch.
* No history of previous orthodontic treatment.

Exclusion Criteria:

* Skeletal class II due to prognathic maxilla.
* Patient with gross facial asymmetry.
* Previous orthodontic or orthopedic treatment.
* Clinical signs and symptoms of any Temporomandibular joint disorders.
* Increased anterior facial vertical dimension.
* Poor oral hygiene.

Where it's running

• Alazhar University in cairo
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed Ha Hablas
• Email: Mohamedhablas1995@gmail.com
• Phone: 01278988226

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Clear twin block for growing patients with class II malocclusion

  This study tests whether wearing a clear twin block appliance for 3 months helps correct dento-skeletal differences in kids aged 9–12 with Class II Division 1 malocclusion.

  Recruiting University of Baghdad · Baghdad, Baghdad Governorate · NCT07924982

• Using infrazygomatic-crest versus interradicular mini-implants to retract upper front teeth in Class II Division 1 malocclusion

  This will test whether mini-implants placed in the infrazygomatic crest or between tooth roots better help pull back the upper front teeth in non-growing patients with Class II Division 1 malocclusion.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07405905

• Conventional versus 3D-printed twin block appliances: bacteria, surface texture, and effectiveness

  This trial will test whether 3D-printed twin block appliances work as well as conventional ones and whether they attract more bacteria or have rougher surfaces in growing children with Class II Division 1 malocclusion.

  Recruiting University of Malaya · Kuala Lumpur, Kuala Lumpur · NCT06944860

• Low-level laser therapy versus piezocision to speed upper canine retraction

  This trial will test whether low-level laser therapy or a small surgical technique called piezocision helps speed maxillary canine retraction in adults (18–25) who need premolar extractions for orthodontic treatment.

  Recruiting Al-Azhar University · Cairo, Cairo Governorate · NCT07466641

• Maxillary Arch Distalization Using Infrazygomatic Crest Miniscrews for Class II Malocclusion

  This study tests if moving the upper dental arch backward with infrazygomatic crest miniscrews safely corrects Class II malocclusion without extra patient cooperation.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07875660

• Custom-made versus ready-made Carriere Motion appliance for correcting Class II bite

  This study will test whether a custom-made Carriere Motion appliance works better than a ready-made version to correct Class II malocclusion in 12–15-year-olds with permanent teeth.

  Recruiting Mansoura University · Al Mansurah, Adakhlia · NCT07361172

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.