Using infrazygomatic-crest versus interradicular mini-implants to retract upper front teeth in Class II Division 1 malocclusion
Official title: MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST VERSUS INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.
Run by Postgraduate Institute of Dental Sciences Rohtak · NCT07405905 · Data updated 2026-11-12
This will test whether mini-implants placed in the infrazygomatic crest or between tooth roots better help pull back the upper front teeth in non-growing patients with Class II Division 1 malocclusion.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak Academic / other |
| Locations | 1 site (Rohtak, Haryana) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | December 2026 |
| Study ends | February 2027 |
| Registry record updated | February 12, 2026 |
| Trial ID | NCT07405905 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are non-growing patients with bilateral Class II molar relationships, all permanent teeth to the second molars present, no or minor maxillary crowding, and a horizontal-to-average growth pattern.
✕Probably not a fit
Patients with prior fixed orthodontic treatment, crossbite, a vertical growth pattern, systemic bone or growth disorders, poor oral hygiene, cleft conditions, or those unwilling to complete follow-up are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, double-blind, non-pharmacological trial compares two mini-implant insertion sites for en-masse retraction after bilateral maxillary first premolar extraction using 0.022" MBT preadjusted edgewise appliances. Patients are randomly assigned to receive either infrazygomatic-crest or interradicular mini-implants as anchorage for retraction of the upper anterior teeth. Outcomes include objective treatment changes in tooth and soft-tissue positions and subjective perceptions from patients and orthodontists. The single-center study is conducted at the Department of Orthodontics and Dentofacial Orthopaedics with oral surgery support at PGIDS Rohtak under institutional ethical approval.
Why it matters
Potential benefit: If successful, the chosen implant placement could make upper-anterior retraction more predictable and efficient, improving lip position and facial profile while providing better anchorage control.
How similar studies have gone: Mini-implants are widely used and have shown effectiveness as anchorage for en-masse retraction, but direct comparisons between infrazygomatic and interradicular placements have produced mixed results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Non growing patients 2. Bilateral Class II molar relationship at pre-treatment. 3. All permanent teeth upto the second molars should be present. 4. No or minor crowding in the maxillary arch. 5. Horizontal to average growth pattern. Exclusion Criteria: 1. Subjects with a history of fixed orthodontic treatment. 2. Crossbite 3. Vertical growth pattern 4. Any systemic disease affecting bone and general growth 5. Poor oral hygiene 6. Cleft patients 7. Patients who fail to follow up or undergo complete treatment
Where it's running
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Post Graduate Institute of Dental Sciences, Rohtak, Haryana 124001
Rohtak, Haryana, India Recruiting
Study contacts
- Study coordinator: Sonal chowdhary, MDS
- Email: sonalsingla@rediffmail.com
- Phone: 9992025599
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.