Turkish Behavioral Indicators of Pain Scale (ESCID) for ventilated ICU patients
Reliability and Validity of the Turkish Version of the Behavioral Indicators of Pain Scale in Mechanically Ventilated Intensive Care Unit Patients
This project will test whether the Turkish version of the Behavioral Indicators of Pain Scale (ESCID) can reliably detect pain in adults on mechanical ventilation who cannot speak.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Saglik Bilimleri Universitesi Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT07467551 on ClinicalTrials.gov |
What this trial studies
Researchers will enroll adult ICU patients who are intubated, mechanically ventilated, nonverbal, and hospitalized at least 24 hours to apply the ESCID during routine care. Trained clinicians will record behavioral indicators and compare measurements to establish reliability (consistency between observers and over time) and validity. Patients with major neurological, hemodynamic, or postoperative complications, those who are unresponsive (RASS -5), or with suspected brain death will be excluded. The work will be conducted at Goztepe Prof Dr Suleyman Yalcin City Hospital with collaboration from national academic partners.
Who should consider this trial
Good fit: Adults (18+) who are intubated, receiving mechanical ventilation, unable to speak (GCS <14), and have been in the ICU at least 24 hours are ideal candidates.
Not a fit: Patients who can self-report pain, those who are unresponsive (RASS -5) or brain-dead, and patients with certain cognitive, psychiatric, or neuromuscular conditions are unlikely to benefit from this scale.
Why it matters
Potential benefit: If successful, this could help clinicians recognize and treat pain more accurately in ventilated ICU patients, improving comfort and clinical outcomes.
How similar studies have performed: Behavioral pain scales have been validated and widely used in mechanically ventilated ICU populations, though validating the ESCID in Turkish is a novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals aged 18 years and older * Patients who are intubated, receiving mechanical ventilation, and unable to establish verbal communication (Glasgow Coma Scale score \<14) * Patients who have been hospitalized in the intensive care unit for at least 24 hours Exclusion Criteria: * Presence of postoperative complications * Hemodynamic instability * History of diagnosed cognitive or psychiatric disorders * History of epilepsy or use of neuromuscular blocking agents * History of spinal cord injury affecting motor function of all four extremities * Individuals with a Richmond Agitation-Sedation Scale (RASS) score of -5 (unresponsive) * Cases with suspected brain death
Where this trial is running
Istanbul
- Goztepe Prof Dr Suleyman Yalcin City Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Mehmet Burak Uyaroğlu, Asst Prof — Fenerbahce University
- Study coordinator: Mehmet Burak Uyaroğlu, Asst Prof
- Email: mburakuyaroglu@gmail.com
- Phone: +905396545352
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.