TSLP in asthma: comparing long and short forms in adults with atopic or severe asthma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will measure and compare the long and short forms of thymic stromal lymphopoietin (TSLP) in adults with asthma. Participants will be adults 18 and older with atopic or severe persistent asthma and will not receive any experimental treatment. Data will come from baseline observations of airway samples and clinical information to explore associations between TSLP isoforms and asthma characteristics. The study is conducted at the Medical University of Warsaw in Poland without an active interventional component.

Why it matters

Who can join: the full rules

1. Inclusion criteria

   * age \> 18 years, without the upper age limit,
   * asthma (diagnosis in accordance with the GINA 2023 guidelines),
2. Exclusion criteria

   * other respiratory diseases (e.g., chronic obstructive pulmonary disease \[COPD\]);
   * active cigarette smoking or a smoking history of \>10 pack-years;
   * active malignancy;
   * active pulmonary tuberculosis or active respiratory tract infection;
   * use of antibiotics within 4 weeks prior to study enrollment;
   * current long-term home oxygen therapy (\>15 hours per day);
   * current treatment with monoclonal antibody therapies (e.g., omalizumab, mepolizumab, reslizumab, dupilumab, tezepelumab, or other biologics);
   * pregnancy.

Where it's running

• Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland,
  Warsaw, Warsaw, Poland Recruiting

Study contacts

• Study coordinator: Izabela Orzołek, MD
• Email: izabela.orzolek@wum.edu.pl
• Phone: +48516223281

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.