Clinical trial Recruiting at 1 site Interventional Ages 18 to 55

Treatment options for gingival recession using different surgical techniques

Official title: Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries Compared With Untreated Contralateral Sites: A Randomized Controlled Clinical Study

Run by Misr International University · NCT05688293 · Data updated 2026-11-12

This study is testing two different surgical methods for treating gum recession in patients with thin gums to see which one works better than just regular non-surgical treatment.

Quick facts

Study typeInterventional
Ages18 Years to 55 Years
SexAll
Enrollment30 (estimated)
SponsorMisr International University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedFebruary 5, 2025
Main results expectedJanuary 20, 2027
Study endsMarch 1, 2027
Registry record updatedJuly 6, 2026
Trial IDNCT05688293 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are medically healthy individuals with a thin gingival phenotype diagnosed with gingival recession type 1.

Probably not a fit

Patients with periodontal disease, smokers, or those with carious teeth will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two surgical techniques, connective tissue graft and de-epithelized free gingival graft, in treating patients with gingival recession type 1. Participants with a thin gingival phenotype will be randomly assigned to one of three groups: one receiving a connective tissue graft, another receiving a free gingival graft, and a control group receiving only non-surgical periodontal treatment. The study will assess changes in gingival thickness and other clinical parameters over a 12-month period. Data will be collected and analyzed to determine the efficacy of the surgical interventions compared to non-surgical treatment alone.

Why it matters

Potential benefit: If successful, this study could provide patients with improved treatment options for gingival recession, leading to better oral health and aesthetics.

How similar studies have gone: Previous studies have shown promising results with similar surgical approaches for gingival augmentation, indicating potential for success in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Medically free patients (American Society of Anesthesiologists I; ASA I)
* Patients diagnosed with recession (RT1)
* Fair oral hygiene
* Patient accepting to provides an informed consent and the follow-up

Exclusion Criteria:

* Carious teeth and teeth with periapical infection.
* Patients diagnosed with periodontitis
* Smokers
* Pregnant and lactating females

Where it's running

  • Faculty of oral and dental medicine, Misr international university
    Cairo, Egypt
    Recruiting

Study contacts

  • Principal investigator: Zainab Hafez, Lecturer — Lecturer, faculty of oral and dental medicine misr international university
  • Study coordinator: Zainab Hafez, Lecturer
  • Email: zeinab.hafez@miuegypt.edu.eg
  • Phone: +01221334637

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.