Treatment of acute stroke caused by carotid artery issues using a specialized stent

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients experiencing acute ischemic stroke due to carotid artery bifurcation stenosis or occlusion. It involves a single-center registry at John Paul II Hospital in Krakow, where patients undergo endovascular treatment with a Micronet-covered CGUARD stent, utilizing neuroprotection techniques such as transient flow reversal. The study aims to gather clinical and imaging data to evaluate the effectiveness of this intervention in a patient population that is often underrepresented in stroke treatment trials.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Consecutive patients with acute ischemic stroke with carotid artery bifurcation stenosis/occlusion as culprit lesion.
* Clinical picture of acute ischemic stroke, stroke-in-evolution, or crescendo TIAs.
* Patient eligible for endovascular stroke therapy according to AHA/ASA stroke management and accepted for emergent stroke intervention by the local NeuroVascular Team Committee according to local standard of practice.
* Signed informed consent form to participate in the study (obtained at the point of first feasibility; note that live-saving procedure track may be executed for performing intervention according to local regulations and routine practice in the center)
* Consent to (routinely performed in this group of patients) follow-up visits that may include imaging as per routine practice in the study center and as clinically indicated.

Exclusion Criteria:

* Known stroke cause other than the carotid bifurcation lesion
* Lack of effective endovascular route needed for intervention
* Any known contraindications to stroke endovascular management

Where it's running

• Department of Cardiac and Vascular Diseases, John Paul II Hospital
  Krakow, Poland Recruiting

Study contacts

• Principal investigator: Piotr Musialek, MD, DPhil — Department of Cardiac and Vascular Diseases, John Paul II Hospital in Krakow
• Study coordinator: Piotr Musialek, MD, DPhil
• Email: pmusialek@szpitaljp2.krakow.pl
• Phone: +48126142287

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.