Treatment for mild to moderate primary open-angle glaucoma using the iStent Infinite device

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of the iStent Infinite Trabecular Micro-Bypass System in adults diagnosed with mild to moderate primary open-angle glaucoma. It is a prospective, multicenter, single-arm study focusing on patients who have not responded to conventional medical and surgical treatments. Participants will be monitored for improvements in intraocular pressure and overall eye health following the intervention. The study aims to provide insights into the safety and efficacy of this innovative device in managing glaucoma.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of primary open-angle glaucoma
* Phakic or pseudophakic
* Age 35 years or older

Exclusion Criteria:

* Traumatic, uveitic, neovascular, angle-closure glaucoma or
* glaucoma associated with vascular disorders
* Active corneal inflammation or edema
* Retinal disorders not associated with glaucoma

Where it's running

• Glaukos Investigator Site
  Cincinnati, Ohio, United States Recruiting

Study contacts

• Study coordinator: Dari Parizadeh
• Email: dparizadeh@glaukos.com
• Phone: 949-481-0575

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Balance training for people with glaucoma

  A randomized study tests whether a structured eight-week balance program helps adults with glaucoma improve balance, reduce fall risk, and lessen fear of falling.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07910955

• Eye drops Rhopressa vs Timolol to protect nerve cells in glaucoma

  In adults with open-angle glaucoma, this study tests whether Rhopressa helps preserve retinal nerve cells better than Timolol while both lower eye pressure.

  Recruiting Phase 4 Indiana University · Bloomington, Indiana · NCT07847073

• Comparison of FT-1000 non-contact tonometry with Goldmann applanation tonometry in glaucoma patients

  This study tests whether the FT-1000 non-contact tonometer gives measurements that agree with the Goldmann applanation tonometer in adults with glaucoma.

  Recruiting Tomey Corporation · Jacksonville, Florida · NCT07804277

• Removing the ripcord from a glaucoma drainage device after 3 months

  This study tests whether removing the ripcord from an implanted glaucoma drainage device changes eye pressure for adults with open-angle glaucoma.

  Recruiting Duke University · Durham, North Carolina · NCT07803536

• Glaucoma and Brain Changes: How Brain Structure and Size See What Glaucoma Is Doing

  This study tests whether glaucoma is linked to broader brain changes by comparing brain MRI and eye health over time in people with glaucoma and matched controls.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT07802769

• Long-Term Results After Ab-interno Trabeculotomy for Glaucoma

  This study tests whether ab-interno trabeculotomy with the Trabectome can provide sustained intraocular pressure reduction in glaucoma patients who had the procedure between 2019 and 2021.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT07780916

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.