Clinical trial Recruiting at 1 site Interventional Ages 21 and up

Treatment for gum recession using a minimally invasive technique

Official title: Treatment of Gingival Recession by Tunnel Technique Using Connective Tissue Graft With or Without Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial

Run by Suez Canal University · NCT06646432 · Data updated 2026-11-12

This study is testing a new way to treat gum recession using a special technique and a growth factor injection to see if it works better than the standard treatment.

Quick facts

Study typeInterventional
Ages21 Years and up
SexAll
Enrollment30 (estimated)
SponsorSuez Canal University
Academic / other
Locations1 site (Ismailia)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedJune 2025
Study endsSeptember 2025
Registry record updatedJanuary 29, 2025
Trial IDNCT06646432 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are systemically healthy adults over 21 years old with Miller class I/II gingival recession.

Probably not a fit

Patients with systemic diseases contraindicating surgical procedures, smokers, or those with poor oral hygiene compliance may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a tunnel technique combined with a connective tissue graft and injectable platelet-rich fibrin for treating Miller class I/II gingival recession. A total of 30 patients will be enrolled, with 15 receiving the treatment with the injectable platelet-rich fibrin and 15 receiving the standard treatment without it. Clinical parameters will be assessed at baseline and after six months, while post-operative pain will be evaluated after ten days. Additionally, histologic examination of the graft will be conducted to determine the saturation of growth factors.

Why it matters

Potential benefit: If successful, this approach could provide a more effective and less invasive treatment option for patients suffering from gingival recession.

How similar studies have gone: Previous studies have shown promising results with similar minimally invasive techniques, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* More than 21 years old
* Systemically healthy
* Presence of Miller class I/II gingival recession
* Presence of identifiable CEJ

Exclusion Criteria:

* Smoking
* Systemic disease that contraindicates surgical procedures.
* Poor compliance with oral hygiene measures
* Necrotizing gingival conditions
* Ongoing active periodontitis

Where it's running

  • Faculty of dentistry, Suez canal university
    Ismailia, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.