Treatment for gum recession using a minimally invasive technique
Official title: Treatment of Gingival Recession by Tunnel Technique Using Connective Tissue Graft With or Without Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
Run by Suez Canal University · NCT06646432 · Data updated 2026-11-12
This study is testing a new way to treat gum recession using a special technique and a growth factor injection to see if it works better than the standard treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Suez Canal University Academic / other |
| Locations | 1 site (Ismailia) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | June 2025 |
| Study ends | September 2025 |
| Registry record updated | January 29, 2025 |
| Trial ID | NCT06646432 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are systemically healthy adults over 21 years old with Miller class I/II gingival recession.
✕Probably not a fit
Patients with systemic diseases contraindicating surgical procedures, smokers, or those with poor oral hygiene compliance may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of a tunnel technique combined with a connective tissue graft and injectable platelet-rich fibrin for treating Miller class I/II gingival recession. A total of 30 patients will be enrolled, with 15 receiving the treatment with the injectable platelet-rich fibrin and 15 receiving the standard treatment without it. Clinical parameters will be assessed at baseline and after six months, while post-operative pain will be evaluated after ten days. Additionally, histologic examination of the graft will be conducted to determine the saturation of growth factors.
Why it matters
Potential benefit: If successful, this approach could provide a more effective and less invasive treatment option for patients suffering from gingival recession.
How similar studies have gone: Previous studies have shown promising results with similar minimally invasive techniques, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * More than 21 years old * Systemically healthy * Presence of Miller class I/II gingival recession * Presence of identifiable CEJ Exclusion Criteria: * Smoking * Systemic disease that contraindicates surgical procedures. * Poor compliance with oral hygiene measures * Necrotizing gingival conditions * Ongoing active periodontitis
Where it's running
-
Faculty of dentistry, Suez canal university
Ismailia, Egypt Recruiting
Study contacts
- Study coordinator: Mohammed Abdel-aziz
- Email: mohamed_naser@dent.suez.edu.eg
- Phone: 00201118580817
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Root coverage using different restorative materials in Class V lesions
This study tests whether using glass ionomer cement, resin composite, or no restoration before root coverage surgery helps people with gum recession and neck lesions
-
Volume-stable collagen matrix vs graft for multiple gingival recessions
This study tests whether a volume-stable collagen matrix can cover exposed roots as well as a traditional graft, in adults with multiple gingival recessions.
-
Gingival recession and its effect on oral health-related quality of life
This project will see how common gingival recession is and whether it affects oral health-related quality of life in adults aged 18–45 who visit a tertiary dental center in Haryana.
-
Comparing a new 3D tunneling technique with a modified coronally advanced tunnel plus connective tissue graft for treating multiple RT2 gingival recession.
This trial will try a new 3D tunneling surgical technique versus a modified coronally advanced tunnel with connective tissue graft to improve root coverage in adults who have multiple RT2 gingival recessions.
-
Using 3D dental imaging to lower gum recession during aligner treatment
This test tries to see if planning aligner treatment with 3D CBCT imaging instead of 2D images can reduce gum recession for adults undergoing dental arch expansion.
-
Gum recession in adults with and without prior orthodontic treatment
We will test which patient and tooth factors increase the chance of gum recession in adults who have or have not had orthodontic treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.