Treatment for gum recession using a minimally invasive technique

Treatment of Gingival Recession by Tunnel Technique Using Connective Tissue Graft With or Without Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial

Not applicable Interventional Suez Canal University · NCT06646432

This study is testing a new way to treat gum recession using a special technique and a growth factor injection to see if it works better than the standard treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages21 Years and up
SexAll
SponsorSuez Canal University Academic / other
Locations1 site (Ismailia)
Trial IDNCT06646432 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of a tunnel technique combined with a connective tissue graft and injectable platelet-rich fibrin for treating Miller class I/II gingival recession. A total of 30 patients will be enrolled, with 15 receiving the treatment with the injectable platelet-rich fibrin and 15 receiving the standard treatment without it. Clinical parameters will be assessed at baseline and after six months, while post-operative pain will be evaluated after ten days. Additionally, histologic examination of the graft will be conducted to determine the saturation of growth factors.

Who should consider this trial

Good fit: Ideal candidates for this study are systemically healthy adults over 21 years old with Miller class I/II gingival recession.

Not a fit: Patients with systemic diseases contraindicating surgical procedures, smokers, or those with poor oral hygiene compliance may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a more effective and less invasive treatment option for patients suffering from gingival recession.

How similar studies have performed: Previous studies have shown promising results with similar minimally invasive techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* More than 21 years old
* Systemically healthy
* Presence of Miller class I/II gingival recession
* Presence of identifiable CEJ

Exclusion Criteria:

* Smoking
* Systemic disease that contraindicates surgical procedures.
* Poor compliance with oral hygiene measures
* Necrotizing gingival conditions
* Ongoing active periodontitis

Where this trial is running

Ismailia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Gingival RecessionTunnelingGingival recessionInjectable platelet rich fibrinMinimally invasive periodontology
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.