Trauma recovery options for veterans: comparing HRV biofeedback and present-centered therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase 2/3 trial compares two PTSD/SUD treatment approaches for veterans in VA care. Participants with PTSD and current substance use difficulties are assigned to trauma-informed Heart Rate Variability Biofeedback or Present-Centered Therapy, delivered during residential programming. The study aims to see if HRV biofeedback improves autonomic regulation and reduces PTSD and SUD symptoms. Outcomes include changes in PTSD symptoms, craving, and substance use, along with safety and feasibility in this setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* PTSD diagnosis
* Enrolled in VA healthcare
* Attending residential programming at CVAMC
* Current substance use difficulty based on screening questions

Exclusion Criteria:

* Non-English speaking
* Inability to complete study procedures
* Lack competency to provide consent
* Acute intoxication of a substance
* Active psychotic symptoms at the study visit
* Suicidal or homicidal ideation with intent and planning
* Pacemaker or other cardiovascular implants.

Where it's running

• Coatesville VA Medical Center
  Coatesville, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Alexander A Puhalla, Ph.D.
• Email: alexander.puhalla@va.gov
• Phone: 610-384-7711

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.