Transcatheter Aortic Valve Replacement Registry for Outcomes and Quality Monitoring
Official title: STS/ACC TVT Registry™
Run by American College of Cardiology · NCT07908355 · Data updated 2026-11-12
This registry collects information from hospitals about patients undergoing TAVR to see how care and outcomes compare to guidelines and nationwide data.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50000 (estimated) |
| Sponsor | American College of Cardiology Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Status | Recruiting |
| Started | September 2026 |
| Main results expected | January 2036 |
| Study ends | January 2036 |
| Registry record updated | November 2, 2026 |
| Trial ID | NCT07908355 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 years and older undergoing transcatheter aortic valve replacement at participating centers.
✕Probably not a fit
Patients treated outside participating centers or without access to the registry data may not benefit from its quality-improvement insights.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The TVT Registry is a national, observational registry created by STS and ACC to benchmark and improve care for patients receiving transcatheter aortic valve replacement. Participating sites submit standardized patient data through the ACC’s NCDR to enable risk-adjusted comparisons, quality improvement, and research. The registry supports pre- and post-market surveillance, monitoring of practice patterns, and evaluation of outcomes across centers. It aims to help hospitals implement guideline-based care and identify opportunities to enhance patient safety and effectiveness of TVT procedures.
Why it matters
Potential benefit: If successful, care providers may identify best practices and improve outcomes for patients undergoing TAVR.
How similar studies have gone: Previous vascular and cardiac device registries have shown value in benchmarking and improving care, though real-world impact varies by site.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 18 years or over on arrival at the facility undergoing transcatheter aortic valve replacement. Exclusion Criteria: \-
Where it's running
-
American College of Cardiology / National Cardiovascular Data Registry
Washington D.C., District of Columbia, United States Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Vericiguat to slow calcific aortic valve narrowing
This trial tests whether vericiguat can slow the progression of mild-to-moderate calcific aortic valve stenosis compared with placebo.
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CHATEAU Registry: Real-world outcomes after TAVR
This registry collects real-world data from adults who had TAVR between 2021 and 2025 to see how they do over time and how valve performance holds up.
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Impact of TAVR on kidney function in people with aortic valve disease
This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.
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Hydra THV Transfemoral Valve Implantation in Severe Aortic Stenosis
This registry tests how safely and effectively the Hydra THV works when implanted through the femoral artery in adults with severe symptomatic aortic stenosis.
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How the type of sedation affects recovery after TAVR
This study will test whether three common sedation approaches (propofol, dexmedetomidine, or midazolam with fentanyl) change how people recover on the first day after transfemoral TAVR.
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How TAVI and M‑TEER affect sleep‑disordered breathing
This will see if adults with aortic stenosis or mitral regurgitation who undergo TAVI or M‑TEER have improvements in sleep‑disordered breathing six months after their procedure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.