Tracking short-term changes in blood metabolites using finger-prick sampling
Official title: Monitoring Changes in Blood Circulating Metabolites Using Minimally Invasive Techniques
Run by Örebro University, Sweden · NCT07527793 · Data updated 2026-11-12
This project will try daily finger-prick microsampling and wearables to see how blood metabolites and glucose change over four weeks in healthy adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 35 (estimated) |
| Sponsor | Örebro University, Sweden Academic / other |
| Locations | 1 site (Örebro) |
| Status | Recruiting |
| Started | January 21, 2026 |
| Main results expected | May 25, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 14, 2026 |
| Trial ID | NCT07527793 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults aged 18–65 with BMI 18.5–29.9, stable weight, non-smokers, not taking routine medications or supplements that interfere with metabolism, and willing to perform daily finger-pricks and wear monitoring devices are ideal.
✕Probably not a fit
People with chronic diseases, recent antibiotic use, active efforts to lose weight, smokers, those on regular medications, or individuals outside the specified age or BMI ranges are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Healthy adults (18–65 years, BMI 18.5–29.9) will be followed for four weeks with daily finger-prick blood microsamples, routine glucose monitoring, dietary records, and wearable activity/sleep trackers. Mass spectrometry-based metabolomics and lipidomics, including isotope-labelled standards, will be used to profile circulating metabolites and capture pre- and postprandial transitions during habitual meals. No dietary or lifestyle interventions are imposed; data are collected under real-life conditions to measure intra- and inter-individual variability. The study also tests the feasibility and robustness of minimally invasive sampling and wearable-derived physiological data for future larger longitudinal studies.
Why it matters
Potential benefit: If successful, this could enable easier, lower-cost metabolic monitoring in daily life and support more personalized nutrition or health tracking without venous blood draws.
How similar studies have gone: Similar pilot work combining microsampling, metabolomics, and wearables has shown promise in capturing postprandial metabolic changes, but broader real-life validations remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age: 18-65 years old 2. Body Mass Index (BMI): 18.5-29.9 kg/m2 3. Weight stability within the previous 3 months (self-reported). 4. Positive intention to maintain usual routine physical activity and eating habits during the study. Exclusion Criteria: 1. Presence of acute chronic diseases, inflammatory or functional gastrointestinal disorders, or any diagnosed disease condition that disrupt daily routine activities. 2. Routine use medications or supplements that could potentially interfere with the study outcomes 3. History of eating disorder 4. Recent use of antibiotic medication within the last 3 months prior to the first visit 5. Active efforts to lose weight 6. Smoking 7. Consumption of alcoholic drinks exceeding nine standard cups per week and/or more than three standard cups per occasion
Where it's running
-
School of Medical Sciences
Örebro, Sweden Recruiting
Study contacts
- Principal investigator: Matej Oresic, Ph.D. — School of Medical Sciences, Orebro University
- Study coordinator: Anh Hoang Nguyen, Ph.D.
- Email: anh-hoang.nguyen@oru.se
- Phone: +46723747116
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.