Tracking antibiotic resistance in patients with cirrhosis and infections
Official title: International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections
Run by Hospital Italiano de Buenos Aires · NCT06634940 · Data updated 2026-11-12
This study looks at how common antibiotic resistance is in patients with cirrhosis who get infections to help create better treatment guidelines for doctors in Latin America.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 17 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Hospital Italiano de Buenos Aires Academic / other |
| Locations | 1 site (Buenos Aires, Buenos Aires F.D.) |
| Status | Recruiting |
| Started | November 15, 2020 |
| Main results expected | December 1, 2030 |
| Study ends | June 1, 2031 |
| Registry record updated | October 10, 2024 |
| Trial ID | NCT06634940 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with cirrhosis who have episodes of culture-confirmed bacterial infections.
✕Probably not a fit
Patients who have undergone solid organ or hematopoietic stem cell transplantation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study monitors the prevalence of antibiotic resistance in patients suffering from cirrhosis who develop bacterial infections. Given that cirrhosis patients are at a heightened risk for serious infections, the study aims to gather data on the types of bacteria causing these infections and their resistance patterns. The findings will help inform empirical antibiotic treatment guidelines specifically tailored for the Latin American region, where current guidelines are lacking. By understanding the local epidemiology of infections, the study seeks to improve patient outcomes through timely and appropriate antibiotic therapy.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for cirrhosis patients facing bacterial infections, potentially reducing mortality rates.
How similar studies have gone: While similar studies have been conducted in other regions, this approach is novel for Latin America, where specific guidelines for antibiotic treatment in cirrhosis patients are currently absent.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Episodes of culture-confirmed bacterial infections * Patients diagnosed with cirrhosis * Infections diagnosed either at the time of hospital admission or during hospitalization Exclusion Criteria: * History of solid organ or hematopoietic stem cell transplantation * Declined to participate in the study
Where it's running
-
Hospital Italiano de Buenos Aires
Buenos Aires, Buenos Aires F.D., Argentina Recruiting
Study contacts
- Study coordinator: Sebastián M Marciano, Principal Investigator.
- Email: sebastian.marciano@hospitalitaliano.org.ar
- Phone: 54 11 49590200
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.