Tracking antibiotic resistance in patients with cirrhosis and infections
International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections
This study looks at how common antibiotic resistance is in patients with cirrhosis who get infections to help create better treatment guidelines for doctors in Latin America.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 17 Years and up |
| Sex | All |
| Sponsor | Hospital Italiano de Buenos Aires Academic / other |
| Locations | 1 site (Buenos Aires, Buenos Aires F.D.) |
| Trial ID | NCT06634940 on ClinicalTrials.gov |
What this trial studies
This study monitors the prevalence of antibiotic resistance in patients suffering from cirrhosis who develop bacterial infections. Given that cirrhosis patients are at a heightened risk for serious infections, the study aims to gather data on the types of bacteria causing these infections and their resistance patterns. The findings will help inform empirical antibiotic treatment guidelines specifically tailored for the Latin American region, where current guidelines are lacking. By understanding the local epidemiology of infections, the study seeks to improve patient outcomes through timely and appropriate antibiotic therapy.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with cirrhosis who have episodes of culture-confirmed bacterial infections.
Not a fit: Patients who have undergone solid organ or hematopoietic stem cell transplantation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for cirrhosis patients facing bacterial infections, potentially reducing mortality rates.
How similar studies have performed: While similar studies have been conducted in other regions, this approach is novel for Latin America, where specific guidelines for antibiotic treatment in cirrhosis patients are currently absent.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Episodes of culture-confirmed bacterial infections * Patients diagnosed with cirrhosis * Infections diagnosed either at the time of hospital admission or during hospitalization Exclusion Criteria: * History of solid organ or hematopoietic stem cell transplantation * Declined to participate in the study
Where this trial is running
Buenos Aires, Buenos Aires F.D.
- Hospital Italiano de Buenos Aires — Buenos Aires, Buenos Aires F.D., Argentina (Recruiting)
Study contacts
- Study coordinator: Sebastián M Marciano, Principal Investigator.
- Email: sebastian.marciano@hospitalitaliano.org.ar
- Phone: 54 11 49590200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.