Clinical trial Recruiting at 1 site Observational Ages 18 and up

Toxicity of intensive first-line treatment for adult Burkitt lymphoma

Official title: Retrospective Observational Study of Intensive First-Line Treatments for Adult Burkitt Lymphoma at Strasbourg University Hospitals

Run by University Hospital, Strasbourg, France · NCT07895927 · Data updated 2026-11-12

This study looks back at adult Burkitt lymphoma patients treated with very aggressive first-line chemotherapy to see how toxic the treatment is and what their long-term outcomes were.

More Burkitt Lymphoma trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment25 (estimated)
SponsorUniversity Hospital, Strasbourg, France
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Strasbourg)
StatusRecruiting
StartedFebruary 11, 2026
Main results expectedFebruary 11, 2027
Study endsApril 11, 2027
Registry record updatedOctober 27, 2026
Trial IDNCT07895927 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with Burkitt lymphoma treated at Strasbourg University Hospitals or ICANS between 2009 and 2025, who have not objected to data reuse.

Probably not a fit

Patients whose data do not show a clear toxicity pattern or those with limited follow-up may not derive actionable insights.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective, single-center observational analysis of adults with Burkitt lymphoma treated at Strasbourg University Hospitals. It aims to characterize short- and long-term treatment-related toxicities, overall survival at five years, and progression-free survival at 24 months. Secondary goals include examining how treatment delays and dose reductions relate to toxicity, and how disease location at diagnosis influences outcomes. Eligibility includes adults diagnosed or managed for Burkitt lymphoma between 2009 and 2025, with consent for reuse of data unless objected. The study uses existing medical records to summarize historical treatment patterns and outcomes.

Why it matters

Potential benefit: If successful, the study could clarify risks of intensive first-line therapy and help inform safer treatment decisions for adults with Burkitt lymphoma.

How similar studies have gone: Prior observational studies have documented high toxicity with intensive regimens; this study adds location-specific, long-term outcome data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 years or older.
* Patients diagnosed with Burkitt lymphoma at Strasbourg University Hospitals between January 1, 2009, and December 31, 2025, and/or managed by the Hematology Department of Strasbourg University Hospitals or ICANS for Burkitt lymphoma during this period.
* No written objection documented in the medical record to the reuse of personal data for scientific research.

Exclusion Criteria:

* Patients who have objected to the reuse of their personal data for scientific research.
* Patients diagnosed with another B-cell non-Hodgkin lymphoma other than Burkitt lymphoma.
* Patients for whom accessible data are unavailable.
* Individuals under legal protection (sauvegarde de justice).
* Individuals under guardianship or curatorship (tutelle or curatelle).

Where it's running

  • Service d'Hématologie et d'Oncologie - CHU de Strasbourg, France
    Strasbourg, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.