Time-restricted eating plus high-intensity interval training to improve metabolic health in adults with overweight or obesity
Time-restricted Eating and High-intensity Interval Training for Long-term Improvement in Metabolic Health
NA · Norwegian University of Science and Technology · NCT07036562
This study will test whether a 12-month program combining time-restricted eating and high-intensity interval training can reduce body fat in adults with overweight or obesity.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Norwegian University of Science and Technology (other) |
| Locations | 1 site (Trondheim) |
| Trial ID | NCT07036562 on ClinicalTrials.gov |
What this trial studies
Adults with a BMI of 27 kg/m² or higher will be randomized to a 12-month periodised time-restricted eating plus remote high-intensity interval training program or to a control group. The intervention is delivered remotely with telephone follow-up, and body composition, fitness, fasting glucose and insulin, lipids, and blood pressure are measured at baseline, 6 months, and 12 months. Additional measures include physical activity, diet, sleep quality, appetite, and adherence, and secondary analyses will examine sex differences in responses. Participants unable to attend in-person measurement visits or who meet exclusion criteria such as diabetes, cardiovascular disease, pregnancy, recent large weight change, or regular high-intensity exercise will be excluded.
Who should consider this trial
Good fit: Adults with overweight or obesity (BMI ≥ 27 kg/m²) who can walk or cycle for at least 60 minutes and who are not pregnant, lactating, on glucose/ lipid/ or hypertension medications, or already doing regular high-intensity exercise are ideal candidates.
Not a fit: People with known diabetes or cardiovascular disease, current use of glucose-, lipid-, or blood-pressure-lowering drugs, recent large weight changes, habitual eating windows of 12 hours or less, night-shift workers, pregnant or recently lactating individuals are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, this combined approach could lower fat mass and improve metabolic markers such as blood glucose, insulin, lipids, and blood pressure.
How similar studies have performed: Previous research has shown that time-restricted eating and high-intensity interval training can each improve metabolic health, but long-term randomized combinations of these approaches are less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Body mass index ≥ 27 kg/m² * Able to walk or ride a bike \> 60 min Exclusion Criteria: * On-going pregnancy * Lactation within 24 weeks of study commencement * High-intensity exercise ≥ 1/week * Habitual eating window ≤12 hours/day * Taking hypertension, glucose-, or lipid-lowering drugs * Body mass variation ≥ 4 kg three months prior to study commencement * Known diabetes mellitus (type 1 or 2) or cardiovascular disease * Working night shifts
Where this trial is running
Trondheim
- Department of circulation and medical imaging, NTNU — Trondheim, Norway (RECRUITING)
Study contacts
- Study coordinator: Kamilla La Haganes, PhD
- Email: kamilla.l.haganes@ntnu.no
- Phone: +4747316765
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Overweight and Obesity, time-restricted eating, high-intensity interval training, exercise, diet, metabolic health, lifestyle intervention