Thyroid size in healthy, full-term newborns

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects thyroid ultrasound measurements from healthy full-term newborns (37–42 weeks gestation) to establish normative thyroid volume values. The goal is to link thyroid size with maternal and neonatal factors and to support newborn screening for congenital hypothyroidism. Ultrasound provides non-invasive, real-time data on gland size, position, and structure to help interpret future findings in clinical settings. Results will help contextualize thyroid measurements in babies who require further screening or investigation. The study emphasizes compliance with consent and exclusion of infants with congenital anomalies or abnormal screening TSH results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy full term newborns (born between 37 and 42 weeks of gestation, with no antennal issue or complications at birth)
* Consent obtained by parent(s) or legal guardian(s)

Exclusion Criteria:

* Congenital malformations
* TSH abnormalities in neonatal screening
* Pregnancy not carried out in Italy, due to different iodine status
* Inability or unwillingness of the parent(s) or legal guardian(s) to provide informed consent or to comply with study procedures

Where it's running

• IRCCS Ospedale San Raffaele
  Milan, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Maria Cristina Vigone, MD
• Email: vigone.mariacristina@hsr.it
• Phone: +39 0226432625

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• How congenital hypothyroidism affects development in infants

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• OptiThyDose for children with congenital hypothyroidism and Graves' disease

  This trial will test whether the OptiThyDose math model helps doctors choose the right thyroid medicine dose for newborns with congenital hypothyroidism and children with Graves' disease.

  Recruiting at 6 sites University Children's Hospital Basel · Yerevan and 6 other locations · NCT06864351

• Exploring genetic causes of congenital hypothyroidism

  This study looks at the genetic causes of congenital hypothyroidism in babies born in Emilia-Romagna, Italy, to see how different genes might affect their condition and future health.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT06728735

• Comparing different levothyroxine formulations for treating congenital hypothyroidism in newborns

  This study is testing which of three different forms of levothyroxine—oral solution, liquid drops, or tablets—works best and is safest for newborns with congenital hypothyroidism.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT06724224

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.