Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Testing for viruses after a monkey bite

Official title: Virus Transmission to People Recently Bitten or With a History of Monkey Bites "SIMVIR"

Run by Institut Pasteur · NCT07097480 · Data updated 2026-11-12

We will test adults who were recently bitten by a monkey or who have a history of monkey bites to see if they carry simian viruses such as STLV-1 or SFV using blood and saliva samples.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment80 (estimated)
SponsorInstitut Pasteur
Industry-sponsored
Locations1 site (Paris)
StatusRecruiting
StartedAugust 14, 2025
Main results expectedDecember 2026
Study endsAugust 2028
Registry record updatedDecember 15, 2025
Trial IDNCT07097480 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) who experienced a WHO category 3 bite from a nonhuman primate, can give written informed consent, and are affiliated with a French social security scheme are ideal candidates.

Probably not a fit

People who only had scratches from nonhuman primates, minors, those under legal protection, or those whose medical care prevents sample collection are unlikely to benefit from joining.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls adults (≥18) who sustained WHO category 3 bites from nonhuman primates, including both recent and past exposures. Participants provide blood and saliva samples, with an optional genetic analysis component for those who consent. Samples will be tested for simian viruses (STLV-1 and SFV) to estimate prevalence and characterize possible transmission after bites. Enrollment and sample processing are conducted at the Institut Pasteur Medical Center in Paris.

Why it matters

Potential benefit: If successful, the study could help identify people who carry simian viruses after monkey bites and improve post-bite monitoring and prevention recommendations.

How similar studies have gone: Field and occupational studies have documented human SFV infections and occasional STLV-1 related findings after primate exposure, but systematic post-bite prevalence studies are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Bite inflicted by an HNP (WHO category 3 level)
* Written informed consent
* Affiliation with a social security scheme (excluding State Medical Aid

Specific criteria for genetic analyses:

* Participant has checked the boxes for participation in the genetic component.

Exclusion Criteria:

* Patient presenting only with scratches inflicted by a PNH
* Medical management incompatible with the objectives of the study
* Patient who, in the doctor's opinion, is unlikely to comply with the study protocol
* Health conditions are incompatible with the sample collection required by the study
* Patient under legal protection (guardianship or trusteeship)

Where it's running

  • Institut Pasteur Medical Center
    Paris, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.