Testing a new brain PET insert for better imaging with MRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to evaluate the feasibility of a dedicated PET insert designed for simultaneous PET/MR imaging of the human brain. The study will involve 40 participants, with half receiving an FDA-approved PET tracer and the other half pre-injected with a radiopharmaceutical for comparison. The performance of the new PET insert will be assessed against a commercial whole-body PET/MRI system using the same radiopharmaceutical. The goal is to enhance imaging capabilities for brain diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Whole body radiation dose within the last year of less than 5000 mrem
2. Subjects intended for injected tracer studies (not associated with another study) must be willing/able to undergo injection of 6-12 mCi of either FDG or Neuraceq radiotracer. Both tracers are FDA approved
3. Subjects will be at least 21 years of age
4. Subject provides written informed consent
5. Subject is deemed healthy by the PI by via self-reported questionnaire

Exclusion Criteria:

1. For patients who will be receiving a tracer injection, no known allergy to the imaging agents
2. Participant has a history of or current diagnosis of cancer
3. Participant is pregnant or nursing
4. Metallic implants (contraindicated for MRI)

Where it's running

• Stanford University
  Palo Alto, California, United States Recruiting

Study contacts

• Study coordinator: Paul Newswanger
• Email: pdn@stanford.edu
• Phone: (650) 736-1349

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.