Testing a brief therapy for insomnia in people recovering from substance use disorders

Using Implementation Science to Examine the Feasibility and Efficacy of Brief Behavioral Therapy for Insomnia (BBTI) in Substance Use Disorder Recovery Programs

Not applicable Interventional Johns Hopkins University · NCT05935735

This study is testing a short therapy for insomnia to see if it can help people recovering from substance use disorders get better sleep while they are in treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorJohns Hopkins University Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT05935735 on ClinicalTrials.gov

What this trial studies

This clinical study aims to evaluate the feasibility and efficacy of Brief Behavioral Therapy for Insomnia (BBTI) in individuals with substance use disorders (SUD) residing in a treatment program. Participants will engage in a 4-week intervention that includes completing surveys, wearing a sleep-monitoring device, and maintaining a sleep diary. The study will assess both subjective and objective sleep outcomes while utilizing the RE-AIM framework to inform the implementation of this therapy in real-world settings. The ultimate goal is to provide evidence supporting the integration of BBTI into SUD recovery programs to enhance treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with active substance use disorders and insomnia, residing at the Helping Up Mission.

Not a fit: Patients with severe medical or psychiatric conditions, those unable to provide informed consent, or individuals with certain sleep disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve sleep quality and recovery outcomes for patients with substance use disorders.

How similar studies have performed: Other studies have shown success with behavioral therapies for insomnia, but this specific application in SUD recovery is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* client of Cornerstone Clinic (CC); resident at Helping Up Mission (HUM)
* active SUD
* ≥ 18 years old
* ISI ≥ 8
* insomnia disorder as determined by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Sleep Disorders (SIS-D)
* able to understand English proficiently

Exclusion Criteria:

* medical or psychiatric condition interfering with treatment or requiring hospitalization
* inability to provide informed consent
* declines behavioral health treatment at CC
* suicidal ideation
* acute alcohol withdrawal requiring medical attention
* pregnant or breastfeeding
* moderate-severe sleep apnea based on WatchPAT
* restless legs syndrome based on SIS-D
* discharged from HUM

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Substance Use DisordersInsomniaBrief Behavioral Therapy for Insomnia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.