Teleprehabilitation program for knee replacement surgery
Official title: The Added Value of Multimodal Biopsychosocial Teleprehabilitation in People Undergoing Total Knee Arthroplasty: a Pilot/Feasibility Trial
Run by Universitair Ziekenhuis Brussel · NCT06565377 · Data updated 2026-11-12
This study is testing a new online program to help people getting knee replacement surgery prepare better and recover faster compared to regular pre-surgery advice.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Universitair Ziekenhuis Brussel Academic / other |
| Locations | 2 sites (Geel, Antwerpen and 1 other locations) |
| Status | Recruiting |
| Started | July 31, 2024 |
| Main results expected | August 31, 2026 |
| Study ends | August 31, 2027 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT06565377 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Dutch-speaking adults over 18 years old who are scheduled for elective primary total knee arthroplasty.
✕Probably not a fit
Patients with significant comorbidities, cognitive impairments, or those undergoing emergency knee surgeries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the feasibility and acceptability of a multimodal biopsychosocial teleprehabilitation program for patients scheduled for total knee arthroplasty. It aims to prepare patients for surgery by providing comprehensive pre-surgical education and rehabilitation strategies through telehealth. The study will compare the effects of this teleprehabilitation approach against standard preoperative advice to assess its impact on patient outcomes. The focus is on enhancing patient readiness and recovery post-surgery.
Why it matters
Potential benefit: If successful, this approach could lead to improved surgical outcomes and faster recovery for patients undergoing knee replacement surgery.
How similar studies have gone: Other studies have shown promising results with teleprehabilitation approaches, indicating potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * People scheduled for elective primary TKA at one of the participating hospitals; * Being over 18 years old; * Dutch speaking/reading Exclusion Criteria: * Doing activities that make them feel out of breath for 300 minutes or more per week on average; * Orthopedic, neurological, cardiovascular or any other condition/comorbidity that leads to an overall contraindication for moderate physical activity; * Cognitive impairment (≥11 on 6-item Cognitive Impairment Test and/or unable to understand the study instructions); * Presence of uncontrolled inflammatory arthritides (e.g., rheumatoid arthritis, gout); * Uncontrolled psychiatric disorders; * Active cancer and/or active cancer treatment ((hormonal) maintenance therapy is allowed); * People undergoing emergency (non-elective) TKA.
Where it's running
-
Ziekenhuis Geel
Geel, Antwerpen, Belgium Recruiting -
Universitair Ziekenhuis Brussel
Brussels, Brussels Capital, Belgium Recruiting
Study contacts
- Principal investigator: Eva Huysmans, PhD — Vrije Universiteit Brussel
- Study coordinator: Eva Huysmans, PhD
- Email: eva.huysmans@vub.be
- Phone: +32 2 477 44 20
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Mind mapping-based education to help after knee replacement
A group of adults having total knee replacement will receive mind-mapping education in addition to standard care to see if it helps with pain, fear of movement, and readiness to leave the hospital.
-
DoACs vs LMWH for blood flow after knee replacement
This study tests whether rivaroxaban, apixaban, or LMWH work differently to support blood flow in the legs after total knee replacement in adults.
-
Branched chain amino acids after knee replacement to help muscle
This trial tests whether giving Livact after knee replacement helps preserve muscle and function in adults with sarcopenia.
-
Cryotherapy to Cut Opioid Use After Knee Replacement
This trial tests whether compressive cryotherapy with a Game Ready device can lower opioid use and improve recovery after total knee replacement in adults 60–80.
-
Early cognitive changes after same-day hip or knee replacement
This study tests whether older adults (65 or older, 70 per description) who have same-day discharge after hip or knee replacement show changes in cognitive test performance from before surgery to the first day after surgery.
-
Preoperative Genicular Nerve Block for Knee Replacement
This study tests whether giving a genicular nerve block before knee replacement can reduce pain after surgery and lower opioid use.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.