Teleprehabilitation program for knee replacement surgery

The Added Value of Multimodal Biopsychosocial Teleprehabilitation in People Undergoing Total Knee Arthroplasty: a Pilot/Feasibility Trial

Not applicable Interventional Universitair Ziekenhuis Brussel · NCT06565377

This study is testing a new online program to help people getting knee replacement surgery prepare better and recover faster compared to regular pre-surgery advice.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversitair Ziekenhuis Brussel Academic / other
Locations2 sites (Geel, Antwerpen and 1 other locations)
Trial IDNCT06565377 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility and acceptability of a multimodal biopsychosocial teleprehabilitation program for patients scheduled for total knee arthroplasty. It aims to prepare patients for surgery by providing comprehensive pre-surgical education and rehabilitation strategies through telehealth. The study will compare the effects of this teleprehabilitation approach against standard preoperative advice to assess its impact on patient outcomes. The focus is on enhancing patient readiness and recovery post-surgery.

Who should consider this trial

Good fit: Ideal candidates are Dutch-speaking adults over 18 years old who are scheduled for elective primary total knee arthroplasty.

Not a fit: Patients with significant comorbidities, cognitive impairments, or those undergoing emergency knee surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and faster recovery for patients undergoing knee replacement surgery.

How similar studies have performed: Other studies have shown promising results with teleprehabilitation approaches, indicating potential for success in this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* People scheduled for elective primary TKA at one of the participating hospitals;
* Being over 18 years old;
* Dutch speaking/reading

Exclusion Criteria:

* Doing activities that make them feel out of breath for 300 minutes or more per week on average;
* Orthopedic, neurological, cardiovascular or any other condition/comorbidity that leads to an overall contraindication for moderate physical activity;
* Cognitive impairment (≥11 on 6-item Cognitive Impairment Test and/or unable to understand the study instructions);
* Presence of uncontrolled inflammatory arthritides (e.g., rheumatoid arthritis, gout);
* Uncontrolled psychiatric disorders;
* Active cancer and/or active cancer treatment ((hormonal) maintenance therapy is allowed);
* People undergoing emergency (non-elective) TKA.

Where this trial is running

Geel, Antwerpen and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Total Knee Arthroplastytotal knee arthroplastyknee replacementprehabilitation
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.