Telephone support programs for people with epilepsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial compares two telephone-based interventions for individuals with epilepsy who experience elevated depressive symptoms. Participants will be randomly assigned to either the UPLIFT program, which focuses on self-management of depression, or the BOOST program, which emphasizes group support. Both interventions consist of eight weekly one-hour sessions and aim to assess changes in depressive symptoms, quality of life, and seizure frequency over a 12-month period. The study will also explore how mindfulness and participant characteristics influence treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* adult (≥18 years of age);
* diagnosed with epilepsy for at least one year;
* fluent in English or Spanish;
* elevated depressive symptoms (PHQ-9 score ≥10);
* willing to participate in audiotaped group telephone sessions

Exclusion Criteria:

* severe depressive symptoms (PHQ-9 ≥20);
* active suicidal ideation (PHQ-9 item #9 ≥1 or otherwise reported during screening);
* active psychotic disorder (psychiatric diagnosis or antipsychotic medications in the EHR);
* significant cognitive impairment (indicated in EHR or evident during screening)

Where it's running

• NYU Langone Health
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Daniel Friedman, MD — NYU Langone Health
• Study coordinator: Tanya Spruill, PhD
• Email: Tanya.Spruill@nyulangone.org
• Phone: 646-501-3429

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.