Telehealth-enhanced hybrid cardiac rehabilitation versus clinic-based rehab after an acute coronary syndrome

Comparing a Novel Telehealth-enabled Hybrid Cardiac Rehabilitation Program to Clinic-based Cardiac Rehabilitation for Improving Patient Engagement and Functional Outcomes After ACS

Not applicable Interventional Columbia University · NCT07541014

This trial tests whether TeleheartCR, a hybrid program combining telehealth, home, and clinic sessions, helps people who had an acute coronary syndrome complete cardiac rehab and improve their fitness as well as traditional clinic-based rehab.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorColumbia University Academic / other
Locations1 site (New York, New York)
Trial IDNCT07541014 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial compares a TeleheartCR hybrid program (up to 36 sessions delivered via a mix of clinic-based and home/telehealth sessions, typically over about 12 weeks) with traditional clinic-based cardiac rehabilitation in patients who experienced an acute coronary syndrome. The study's primary implementation outcome is program adherence, and the primary effectiveness outcome is non-inferior pre-to-post change in functional capacity; secondary outcomes include quality of life and cardiorespiratory fitness. Participants are adults (≥18) within 12 months of ACS, able to read English or Spanish, and residing in New York State; some clinic visits at Columbia University Irving Medical Center are required. The protocol allows scheduling flexibility with up to 6 months post-enrollment to complete the program to accommodate clinical and personal needs.

Who should consider this trial

Good fit: Adults 18 or older who had an acute coronary syndrome within the past 12 months, are eligible for outpatient cardiac rehabilitation, can read English or Spanish, and live in New York State are ideal candidates.

Not a fit: People with high exercise-related cardiovascular risk, severe medical or psychiatric comorbidities, unsafe home environments, those who already started cardiac rehab, or those living outside New York State are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, TeleheartCR could increase access and adherence to cardiac rehabilitation while preserving the same functional and quality-of-life benefits as clinic-based programs.

How similar studies have performed: Previous studies of home-based or telehealth cardiac rehab have shown promising or non-inferior results for fitness and adherence, though hybrid programs focused on implementation and equity are less extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Diagnosis of acute coronary syndrome within the past 12 months
* Eligible for outpatient cardiac rehabilitation
* Able to read and speak English or Spanish
* Resides in New York State

Exclusion Criteria:

* Severe medical or psychiatric comorbidities that would prevent safe or adequate participation
* High risk for adverse exercise-related cardiovascular events
* Initiation of cardiac rehabilitation prior to enrollment (i.e., \>1 session completed)
* Conditions that would interfere with safe or consistent participation in study procedures
* Home environment or willingness not compatible with safe or adequate participation
* Not expected to be available for follow-up during the study period
* Current participation in another interventional clinical trial that may affect study outcomes

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Coronary SyndromeMyocardial InfarctionCardiac RehabilitationHybrid Cardiac RehabilitationVirtual Cardiac RehabilitationImplementation ScienceAdherenceFunctional Capacity
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.