Clinical trial Recruiting at 1 site Interventional Ages 45 to 70

Task-oriented training vs. hand-arm bimanual therapy in stroke recovery

Official title: Comparative Effects of Task-Oriented Training and Hand-Arm Bimanual Intensive Therapy on Gross and Fine Motor Skills of Upper Limb and Activities of Daily Living in Post-Stroke Patients

Run by Riphah International University · NCT07724925 · Data updated 2026-11-12

This study tests whether task-focused practice or intensive two-handed arm therapy helps improve hand and arm skills and daily activities after a stroke.

Quick facts

Study typeInterventional
Ages45 Years to 70 Years
SexAll
Enrollment30 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Nankana Sahib)
StatusRecruiting
StartedJune 1, 2025
Main results expectedJuly 30, 2026
Study endsAugust 2, 2026
Registry record updatedJuly 24, 2026
Trial IDNCT07724925 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 45–70 with a first-time stroke (ischemic or hemorrhagic) at least 3 months prior and mild-to-moderate upper-limb impairment who can follow commands.

Probably not a fit

Patients with severe spasticity, significant cognitive impairment, or unstable medical conditions may not benefit from these interventions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two rehabilitation approaches for adults who have had a stroke: task-oriented training and hand-arm bimanual intensive therapy. Thirty participants aged 45–70 with mild-to-moderate upper-limb impairment will be randomized to receive one of the two therapies over eight weeks at DHQ Hospital Nankana Sahib. Outcomes include the Action Research Arm Test for gross movement, the Nine Hole Peg Test for fine motor skills, and the Barthel Index for daily living activities, assessed before and after the intervention. Data will be analyzed with SPSS, using appropriate statistical tests and a 0.05 significance level. Normality will be checked, and analyses will consider group differences and within-group changes.

Why it matters

Potential benefit: If successful, the preferred therapy could offer clearer guidance on how to maximize arm function and independence after stroke.

How similar studies have gone: Previous rehabilitation trials have reported improvements with both task-oriented and bimanual therapies, supporting the potential value of this head-to-head comparison.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Age 45-70

  * Gender (both male and female)
  * Pre diagnosed First-time stroke patients (ischemic or hemorrhagic)
  * Time since stroke: ≥3 months
  * Mild to moderate upper limb impairment (ABILHAND Questionnaire: Less than 50% of items rated as "impossible.")
  * Moderate functional independence in basic activities (Barthel Index score ≥ 60)
  * Ability to follow commands (MMSE \> 24 or equivalent cognitive screening)

Exclusion Criteria:

* • Severe spasticity (Modified Ashworth Scale score ≥ 3) or contractures

  * Other neurological conditions (Alzheimer's disease, Parkinson and dementia)
  * Unstable medical conditions (diabetes and hypertension) that may interfere with participation
  * Participation in any other structured upper limb rehabilitation or experimental therapy within the past 3 months

Where it's running

  • DHQ Hospital Nankana Sahib
    Nankana Sahib, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.