Ideomotor Apraxia and Robotic Gait Rehabilitation Outcomes After Stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, prospective observational cohort study at Izmir City Hospital. It will classify participants by ideomotor apraxia status using the Test of Upper Limb Apraxia (TULIA) before rehabilitation. All participants receive routine rehabilitation plus RehaWalk-supported gait training (three sessions per week for up to five weeks) and will be assessed at baseline and after the 15th session or at discharge. The main goal is to determine whether baseline apraxia is independently associated with functional gains measured during standard care; outcome assessors will be blinded to apraxia status. No experimental treatments are administered; the study observes routine care to understand prognostic relationships.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 years or older.
2. Clinically and radiologically confirmed ischemic or hemorrhagic stroke.
3. Scheduled to receive robotic gait rehabilitation as part of routine clinical care.
4. At least 1 month since stroke onset.
5. Ability to walk at least 10 meters with or without an assistive device.
6. Ability to stand independently or under supervision for at least 2 minutes.
7. Brunnstrom lower extremity recovery stage of 3 or higher.
8. Modified Ashworth Scale score below 3 for the plantar flexor muscle group.
9. Sufficient upper extremity motor function to permit TULIA assessment, defined as a Fugl-Meyer Assessment upper extremity motor score of at least 20.
10. Sufficient cognitive ability to understand the study assessments, defined as a Mini-Mental State Examination score of at least 18.
11. Ability to understand the informed consent form and provide written informed consent.

Exclusion Criteria:

1. Failure to provide written informed consent or withdrawal of consent.
2. Severe aphasia or advanced cognitive impairment preventing understanding or completion of the study assessments.
3. Severe unilateral neglect.
4. Cerebellar stroke.
5. Parkinson's disease, multiple sclerosis, motor neuron disease, or another neurological disorder that may affect walking.
6. Orthopedic disease or previous surgery substantially affecting lower extremity function, including advanced osteoarthritis, lower extremity amputation, unhealed fracture, or severe contracture.
7. Severe plantar flexor spasticity, defined as a Modified Ashworth Scale score of 3 or higher.
8. Cardiovascular or systemic disease preventing safe participation in robotic gait rehabilitation, including unstable angina, uncontrolled arrhythmia, decompensated heart failure, uncontrolled hypertension, acute infection, or severe respiratory failure.
9. Conditions preventing safe use of the gait rehabilitation system, including inability to use the safety belt or suspension system appropriately, severe lower extremity deformity, serious skin lesions or pressure ulcers, or height or body weight outside the manufacturer's specified limits.
10. Severe visual or hearing impairment preventing reliable administration of the assessments.
11. Any condition judged by the investigator to make participation unsafe or prevent compliance with the study protocol.

Where it's running

• Izmir City Hospital
  Izmir, İzmir, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Ertan Yılmaz, MD — Izmir City Hospital
• Study coordinator: Aylin Dikici, MD
• Email: aylinkaraman401@hotmail.com
• Phone: +90 506 484 34 42

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.