Tai Chi versus Modified-Otago exercises for pain, balance, and walking in diabetic peripheral neuropathy
Official title: Comparative Effects of Tai Chi Versus Modified-Otago Exercises On Pain, Balance And Motor Function In Patients With Diabetic Peripheral Neuropathy
Run by Riphah International University · NCT07078565 · Data updated 2026-11-12
This trial will test whether Tai Chi or Modified-Otago exercises better reduce pain and improve balance and movement in people with diabetic peripheral neuropathy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 80 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | January 25, 2025 |
| Main results expected | November 30, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | July 22, 2025 |
| Trial ID | NCT07078565 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 40–80 with type 2 diabetes for at least 5 years, chronic neuropathic pain for ≥6 months with pain ≥3 on the NPRS and a Toronto Clinical Neuropathy Score ≥6, who are ambulatory and free of active foot ulcers or major neurologic disease are ideal candidates.
✕Probably not a fit
Non-ambulatory patients, those with active foot ulceration or infection, or those with major neurologic conditions such as stroke, Parkinson's disease, or multiple sclerosis are unlikely to benefit or be eligible for this trial.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial enrolls 36 adults with type 2 diabetes and confirmed diabetic peripheral neuropathy to compare two structured exercise programs. Participants aged 40–80 who meet neuropathy and pain thresholds are randomly assigned to a Tai Chi group or a Modified-Otago strength-and-balance group and complete supervised exercise sessions. Primary outcomes include changes in pain, balance, and motor function measured by standard clinical scales and performance tests. The trial offers a non-drug approach to symptom management delivered at a single rehabilitation center.
Why it matters
Potential benefit: If successful, these exercise programs could reduce chronic neuropathic pain, improve balance and walking ability, and lower fall risk for people with diabetic peripheral neuropathy.
How similar studies have gone: Prior studies in older adults and some diabetes cohorts have shown Tai Chi and Otago-like programs can improve balance and reduce fall risk, but direct head-to-head comparisons in diabetic peripheral neuropathy are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Both genders are aged 40-80 years * Patient having Types ii diabetes with Minimum of 5 years since diabetes diagnosis * Patients experiencing chronic pain for at least 6 months and level ≥ 3 on NPRS. * Patient having ≥ 6 score on Toronto Clinical Neuropathy Scoring System for diabetic neuropathy Exclusion Criteria: * Non-ambulatory patients * Patients with ulceration/infection of feet, medical/surgical conditions * Patients suffering from stroke, parkinson's disease, or multiple sclerosis
Where it's running
-
Riphah Rehab Training and Research Center,
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Amna Shahid, t-DPT — Riphah International University
- Study coordinator: Imran Amjad, PhD
- Email: imran.amjad@riphah.edu.pk
- Phone: 03324390125
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.