Sutureless hemorrhoidectomy vs conventional ligation for advanced hemorrhoids

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective randomized trial, adults with symptomatic Grade III–IV hemorrhoidal disease are assigned to either sutureless hemorrhoidectomy using an energy-based vessel sealing device or the conventional Milligan-Morgan ligation method. The study aims to compare perioperative and postoperative outcomes, including pain, bleeding, wound healing, complications, return to normal activities, and recurrence over a 6-month follow-up. Standardized analgesia and postoperative care are provided, with follow-ups at 1 week, 2 weeks, 1 month, 3 months, and 6 months. Conducted at Sohag University Hospital, the trial enrolls 50 participants (25 per arm) to determine if the sutureless approach offers advantages in recovery and safety. Outcomes will inform whether energy-based sutureless techniques can become preferred options for advanced hemorrhoidal surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aged 18 years or older.
* Patients with symptomatic grade III or grade IV hemorrhoidal disease.
* Combined internal and external hemorrhoidal disease requiring excisional hemorrhoidectomy.
* Recurrent bleeding, prolapse, pain, mucous discharge, or hygiene difficulty despite conservative or office-based treatment.

Exclusion Criteria:

* Patients younger than 18 years.
* Grade I or grade II hemorrhoids suitable for conservative or office-based therapy.
* Acute thrombosed external hemorrhoids requiring emergency management.
* Associated anal fissure, fistula-in-ano, perianal abscess, or inflammatory bowel disease.
* Suspected or confirmed colorectal malignancy\[cite: 1\].
* History of previous anorectal surgery\[cite: 1\].
* Bleeding diathesis, uncontrolled anticoagulant therapy, or severe coagulopathy\[cite: 1\].

Where it's running

• Sohag University Hospital, Department of General Surgery
  Sohag, Egypt Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Trans-radial superior rectal artery embolisation for bleeding haemorrhoids

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.