Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Surgical treatment for gum tissue issues after removing localized growths

Official title: Periodontal Plastic Surgical Approaches to Correct Recession and Lack of Keratinized Tissue After Elimination of Localized Gingival Enlargements - a Case Series

Run by Semmelweis University · NCT06210789 · Data updated 2026-11-12

This study is testing a new surgical method to help people with gum problems after removing growths, aiming to improve their gum health and reduce complications.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment22 (estimated)
SponsorSemmelweis University
Academic / other
Locations1 site (Budapest)
StatusRecruiting
StartedJanuary 5, 2024
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedApril 4, 2025
Trial IDNCT06210789 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are systematically healthy adults over 18 with localized gingival enlargement affecting a maximum of three teeth.

Probably not a fit

Patients who are pregnant, heavy smokers, or taking medications that affect oral mucosa healing may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial focuses on addressing non-inflammatory recessions and mucogingival defects that occur after the surgical removal of localized gingival enlargements. The study employs techniques such as the subperiosteal envelope technique combined with connective tissue grafts to enhance keratinized tissue and promote root coverage. By evaluating the effectiveness of these surgical interventions, the trial aims to reduce postoperative complications like recurrence and gingival recessions. The goal is to improve oral hygiene maintenance and overall periodontal health for affected patients.

Why it matters

Potential benefit: If successful, this approach could significantly improve periodontal health and reduce complications for patients with localized gingival enlargements.

How similar studies have gone: Previous studies have shown promise with similar surgical techniques, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients older than 18 years
* systematically healthy patients
* localized gingival enlargement is present that involves maximum 3 teeth

Exclusion Criteria:

* pregnant women
* medication intake that can potentially affect the oral mucosa and its healing
* heavy smokers (\>=15)

Where it's running

  • Semmelweis University, Faculty of Dentistry
    Budapest, Hungary
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.