Surgical approach for treating advanced gum disease with grafting
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Enamel Matrix Derivated and Xenograft for the Treatment of Periodontal Defects: A Controlled Clinical Trial
This study is testing a new surgical technique for people with advanced gum disease to see if it helps their gums heal better and improves their overall dental health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universidad de Murcia Academic / other |
| Locations | 1 site (Murcia) |
| Trial ID | NCT03997578 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a modified surgical technique called Non-incised Papillae Surgical Approach (NIPSA) combined with connective tissue grafts and Emdogain for patients suffering from advanced periodontal disease. The goal is to improve treatment outcomes for individuals with significant periodontal support loss. Patients with specific periodontal conditions will undergo this innovative approach to assess its efficacy in enhancing healing and regeneration of periodontal tissues.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with periodontitis who have specific periodontal lesions and probing depths.
Not a fit: Patients with systemic diseases that contraindicate treatment or those with third molars will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved healing and better long-term outcomes for patients with advanced periodontal disease.
How similar studies have performed: While this approach is innovative, similar surgical techniques have shown promise in improving periodontal outcomes, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients diagnosed with periodontitis. * plaque index and bleeding index of \< 30%. * periodontal lesions with pocket probing depth \> 5 mm. * intrabony defect \> 3 mm. * intrabony defect configuration including a 1 and/or 2-wall component, always involving the buccal wall. Exclusion Criteria: * patients with systemic diseases that contraindicated treatment. * third molars. * teeth with incorrect endodontic or restorative treatment.
Where this trial is running
Murcia
- Centro Odontologico Del Sureste Slp — Murcia, Spain (Recruiting)
Study contacts
- Study coordinator: Antonio J Ortiz-Ruiz, MD
- Email: ajortiz@um.es
- Phone: +34868888581
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.