Subcutaneous Tissue Closure After Abdominal Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, patient- and assessor-blinded, single-center study comparing subcutaneous tissue closure with interrupted Vicryl 2-0 sutures versus not closing the subcutaneous tissue after an abdominal incision of at least 6 cm. Adults undergoing elective open or minimally invasive abdominal surgery are randomized after fascial closure to receive or not receive subcutaneous suturing. The trial aims to determine if subcutaneous closure reduces surgical site infection and improves wound healing compared with not closing this tissue layer. Outcomes include postoperative infections and related wound-healing complications, patient recovery, and healthcare utilization. The study is conducted at University Hospital Augsburg and is designed as a superiority trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (≥18 years)
* elective laparotomy (midline laparotomy, transverse laparotomy, subcostal incision, thoracoabdominal incision, or extended Pfannenstiel incision) or laparoscopically assisted abdominal surgery with a specimen extraction incision of at least 6 cm.

Exclusion Criteria:

* Emergency laparotomy.
* Anticipated or documented non-compliance with study procedures or follow-up.
* Patients in whom primary wound closure cannot be achieved at the end of surgery.
* Patients unable to provide informed consent.

Where it's running

• University Hospital Augsburg
  Augsburg, Bavaria, Germany Recruiting

Study contacts

• Principal investigator: Johannes Lauscher, Prof. Dr. med. — Klinik für Allgemein-, Viszeral-, Transplantations- und Thoraxchirurgie
• Study coordinator: Florian Schepp, Dr. med.
• Email: florian.schepp@uk-augsburg.de
• Phone: +490821400168803

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Prophylactic subcutaneous drainage after gynecologic cancer surgery

  This study tests whether placing a small drain under the skin after gynecologic cancer surgery helps prevent wound problems in women with thicker tissue under the skin.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul · NCT07735962

• Bedside ultrasound to detect early post‑laparotomy wound fluid and predict infection

  This project will try bedside ultrasound on adults after open abdominal surgery to see if early fluid under the skin predicts a surgical site infection.

  Recruiting at 3 sites Slagelse Hospital · Herlev, Capital Region and 2 other locations · NCT07549880

• Skin glue plus buried stitch versus buried stitch alone for cesarean wound closure

  This trial tests whether adding skin glue to the buried stitch improves wound healing, scar appearance, and patient satisfaction after elective cesarean delivery in adults.

  Recruiting Hadassah Medical Organization · Jerusalem · NCT07483411

• Clindamycin cream versus povidone-iodine vaginal cleansing to prevent infections after cesarean

  This compares clindamycin vaginal cream to 10% povidone-iodine vaginal cleansing before an elective cesarean to see if one prevents post‑operative infections better.

  Recruiting Phase 4 Beni-Suef University · Banī Suwayf · NCT07474194

• Predicting and preventing surgical wound infections after brain or spinal tumor surgery

  This trial will test whether a machine-learning tool that flags people having brain or spine tumor surgery for extra infection-prevention care can lower their risk of surgical wound infections.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, PUMC · NCT07378683

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.