Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Skin glue plus buried stitch versus buried stitch alone for cesarean wound closure

Official title: Intracuticular Suture Alone Compared to Intracuticular Suture and Skin Adhesive Material for Skin Closure After Cesarean Delivery : a Prospective Randomized Control Study

Run by Hadassah Medical Organization · NCT07483411 · Data updated 2026-11-12

This trial tests whether adding skin glue to the buried stitch improves wound healing, scar appearance, and patient satisfaction after elective cesarean delivery in adults.

More Surgical Site Infection (SSI) trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment240 (estimated)
SponsorHadassah Medical Organization
Academic / other
Locations1 site (Jerusalem)
StatusRecruiting
StartedJanuary 27, 2025
Main results expectedJanuary 27, 2027
Study endsAugust 1, 2027
Registry record updatedApril 2, 2026
Trial IDNCT07483411 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) scheduled for an elective, term cesarean section at Hadassah University Medical Center (37+0 to 41+6 weeks) with no prior wound-healing problems are the ideal participants.

Probably not a fit

Women undergoing emergency or preterm cesarean sections or those with prior cesarean wound complications are excluded and unlikely to benefit from this trial's findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial at Hadassah University Medical Center will assign adults having elective cesarean section to either intracuticular (buried) monofilament suture alone or the same suture plus a biological skin adhesive (Dermabond). The primary outcome is the rate of skin scar complications, and secondary outcomes include patient satisfaction, convenience, and scar healing and appearance. Participants will complete a questionnaire on postoperative day 2 and attend clinical follow-up to document outcomes. The trial enrolls term elective cesarean deliveries (37+0 to 41+6 weeks) and excludes emergency or preterm procedures and patients with prior wound complications.

Why it matters

Potential benefit: If successful, the combined glue-and-suture approach could reduce wound complication rates and produce better-looking scars with higher patient satisfaction after cesarean delivery.

How similar studies have gone: Previous trials comparing skin glue and subcuticular sutures for cesarean or other surgical skin closures have reported mixed results, with some improvements in cosmesis but no consistent superiority.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing elective cesarean section at Hadassa medical center
* Patients undergoing elective cesarean section btween 37+0/7 and 41+6/7 weeks of gestation

Exclusion Criteria:

* Patients undergoing emergency cesarean section
* patients undergoing cesarean section before 37+0/7 weeks of gestation
* patients with a history of previous wound complications after previous Caesarean section

Where it's running

  • Hadassah University Medical Center, Ein Karem Campus
    Jerusalem, Israel
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.