Skin glue plus buried stitch versus buried stitch alone for cesarean wound closure
Intracuticular Suture Alone Compared to Intracuticular Suture and Skin Adhesive Material for Skin Closure After Cesarean Delivery : a Prospective Randomized Control Study
This trial tests whether adding skin glue to the buried stitch improves wound healing, scar appearance, and patient satisfaction after elective cesarean delivery in adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 240 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Hadassah Medical Organization Academic / other |
| Locations | 1 site (Jerusalem) |
| Trial ID | NCT07483411 on ClinicalTrials.gov |
What this trial studies
This randomized trial at Hadassah University Medical Center will assign adults having elective cesarean section to either intracuticular (buried) monofilament suture alone or the same suture plus a biological skin adhesive (Dermabond). The primary outcome is the rate of skin scar complications, and secondary outcomes include patient satisfaction, convenience, and scar healing and appearance. Participants will complete a questionnaire on postoperative day 2 and attend clinical follow-up to document outcomes. The trial enrolls term elective cesarean deliveries (37+0 to 41+6 weeks) and excludes emergency or preterm procedures and patients with prior wound complications.
Who should consider this trial
Good fit: Adults (≥18 years) scheduled for an elective, term cesarean section at Hadassah University Medical Center (37+0 to 41+6 weeks) with no prior wound-healing problems are the ideal participants.
Not a fit: Women undergoing emergency or preterm cesarean sections or those with prior cesarean wound complications are excluded and unlikely to benefit from this trial's findings.
Why it matters
Potential benefit: If successful, the combined glue-and-suture approach could reduce wound complication rates and produce better-looking scars with higher patient satisfaction after cesarean delivery.
How similar studies have performed: Previous trials comparing skin glue and subcuticular sutures for cesarean or other surgical skin closures have reported mixed results, with some improvements in cosmesis but no consistent superiority.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing elective cesarean section at Hadassa medical center * Patients undergoing elective cesarean section btween 37+0/7 and 41+6/7 weeks of gestation Exclusion Criteria: * Patients undergoing emergency cesarean section * patients undergoing cesarean section before 37+0/7 weeks of gestation * patients with a history of previous wound complications after previous Caesarean section
Where this trial is running
Jerusalem
- Hadassah University Medical Center, Ein Karem Campus — Jerusalem, Israel (Recruiting)
Study contacts
- Study coordinator: Efrat Shekel, MD
- Email: efratsh14@gmail.com
- Phone: +972507680404
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.