Long-Term Epilepsy Outcomes in Children After Perinatal Stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective, multicenter observational study involving children and young adults who experienced a stroke before 28 days of age. Researchers will review medical records from Strasbourg and Necker Hospital to describe long-term epilepsy outcomes, including focal epilepsy, infantile spasms, CSWS, and Lennox-Gastaut syndrome. The goal is to relate initial stroke characteristics to later epilepsy courses and treatment needs. No interventions are being tested; the study purely observes and documents historical data. Results could inform prognosis and follow-up planning for affected children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Minors aged 5 to under 18 years or adults aged 18 to 25 years.
* Patients who attended one of the two participating centers: Strasbourg University Hospitals or Necker Hospital (AP-HP).
* Confirmed or suspected ischemic or hemorrhagic stroke occurring before 28 days of age.
* During follow-up, presentation of criteria for focal epilepsy, infantile spasms, continuous spike-and-wave during sleep (CSWS), or Lennox-Gastaut syndrome.

Exclusion Criteria:

* Birth before 34 weeks of gestation.
* Birth weight below 1,500 g.
* Perinatal hypoxic-ischemic injury with residual MRI lesions.
* Insufficient information in medical records.
* Refusal to participate in the study.

Where it's running

• Service de Pédiatrie 1 - Hôpital de Hautepierre - CHU de Strasbourg, France
  Strasbourg, France Recruiting

Study contacts

• Study coordinator: Sarah Baer, MD
• Email: sarah.baer@chru-strasbourg.fr
• Phone: 33 3 88 12 84 98

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.