Clinical trial Recruiting at 1 site Interventional Ages 18 to 90

Structured inpatient physiotherapy before and after CABG for high-risk patients

Official title: Effect of a Preoperatively Initiated Structured Inpatient Physiotherapy Program on Postoperative Outcomes in High-Risk Coronary Artery Bypass Grafting Patients

Run by Bezmialem Vakif University · NCT07725887 · Data updated 2026-11-12

This trial tests whether starting a structured inpatient physiotherapy program at least two days before CABG and continuing after surgery helps high-risk patients recover faster than the same program used only after surgery.

Quick facts

Study typeInterventional
Ages18 Years to 90 Years
SexAll
Enrollment100 (estimated)
SponsorBezmialem Vakif University
Academic / other
Locations1 site (Istanbul, Eyupsultan)
StatusRecruiting
StartedJuly 22, 2026
Main results expectedJanuary 2, 2027
Study endsJanuary 3, 2027
Registry record updatedJuly 24, 2026
Trial IDNCT07725887 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older scheduled for elective CABG who are high-risk by meeting at least three criteria (LVEF <40%, three-vessel disease, multiple comorbidities, smoking history, or age >65).

Probably not a fit

Patients who are unable to participate in preoperative sessions or have exclusions such as planned redo CABG, severe mobility limitations, or other contraindications may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

High-risk patients undergoing CABG often have longer recoveries. This study compares two physiotherapy approaches: a structured inpatient program started before surgery and continued afterward versus the same program started only after surgery. Both groups receive breathing exercises, mobilization, and related techniques, but the preoperative start may influence recovery metrics. The primary outcome is hospital length of stay, with secondary outcomes including ICU stay, inflammatory markers, anemia, and patient-reported dyspnea and fatigue. Conducted at Bezmialem Vakif University, the study aims to clarify whether preoperative rehabilitation enhances postoperative recovery in this high-risk population.

Why it matters

Potential benefit: If successful, patients could experience shorter hospital stays and faster overall recovery after CABG.

How similar studies have gone: Previous preoperative rehabilitation studies show promise but have been limited by heterogeneity; this trial uses a standardized program.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 years or older.
* Scheduled to undergo elective coronary artery bypass grafting (CABG).
* High-risk patients meeting at least three of the following criteria:

Left ventricular ejection fraction (LVEF) \<40%. Three-vessel coronary artery disease. More than two comorbidities. History of smoking. Age \>65 years.

\- Able and willing to provide written informed consent.

Exclusion Criteria:

* Planned redo CABG surgery.
* Severe neurological or orthopedic conditions limiting mobilization.
* Severe cognitive impairment.
* Hemodynamic instability.
* Contraindications to mobilization or exercise.
* Inability to complete at least two days of the preoperative physiotherapy program.

Where it's running

  • Bezmialem Vakif University
    Istanbul, Eyupsultan, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.