Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Structured Active Follow-up After Thyroid Surgery

Official title: Comparative Effectiveness of Structured Active Follow-up Versus Conventional Passive Follow-up in Postoperative Management of Thyroid: A Prospective Cohort Study

Run by West China Hospital · NCT07589660 · Data updated 2026-11-12

This study tests a structured, proactive follow-up program to help people after thyroid cancer surgery manage medications, monitor for recurrence, and address complications.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment244 (estimated)
SponsorWest China Hospital
Academic / other
Locations1 site (Chengdu, Sichuan)
StatusRecruiting
StartedJanuary 31, 2026
Main results expectedApril 1, 2027
Study endsApril 1, 2028
Registry record updatedAugust 19, 2026
Trial IDNCT07589660 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–75 who had thyroid surgery at the study center and have the means to participate in online follow-up.

Probably not a fit

Patients unable to participate in online follow-up or with conditions requiring frequent hospital visits may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates a structured active follow-up program for adults who have recently undergone thyroid surgery. The program aims to improve adherence to long-term monitoring, facilitate timely medication adjustments, and detect complications such as hypoparathyroidism or vocal cord issues. Eligible participants are 18 to 75 years old, speak Chinese, and have the necessary smartphone and internet access to participate in online follow-up visits. The study is conducted at West China Hospital of Sichuan University and is led by Yu Feng. Key outcomes will include follow-up adherence and potential improvements in postoperative management and survival-related indicators over at least one year.

Why it matters

Potential benefit: If successful, participants may experience better monitoring, timely treatment adjustments, and potentially improved long-term outcomes after thyroid surgery.

How similar studies have gone: Previous data support that structured follow-up can improve adherence and outcomes in thyroid dysfunction, though this specific online active-follow-up approach is newer.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18-75 years (including 18 and 75 years)
* Patients who have undergone thyroid surgery (including endoscopic surgery, open surgery, etc.) at this study center
* Patients who are conscious, able to communicate in Chinese, and have the necessary smartphone and internet skills to complete outpatient visits (to meet the online functionality requirements of the active follow-up program)
* Patients who voluntarily agree to participate in the study and are able to sign the informed consent form

Exclusion Criteria:

* Patients with other serious illnesses requiring frequent hospital visits or long-term hospitalization (e.g., advanced malignant tumors, severe heart failure, etc.) that may interfere with the assessment of follow-up adherence
* Patients with anaplastic thyroid cancer or distant metastasis, who have an extremely short life expectancy and cannot complete one year of follow-up
* Patients with cognitive impairment or mental illness who are unable to complete the questionnaires
* Patients who plan to move out of the local area within 2 years after surgery and are unable to complete long-term follow-up
* Patients who are pregnant, lactating, or planning to become pregnant within one year
* Patients currently participating in another clinical study that may interfere with their participation in this study

Where it's running

  • West China hospital of Sichuan University
    Chengdu, Sichuan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.