Steerable Ureteroscopic Renal Evacuation (SURE) with CVAC vs standard ureteroscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized study compares two ureteroscopy approaches for treating kidney stones: Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC system versus conventional ureteroscopy with laser lithotripsy. Participants are assigned 1:1 across multiple centers and will undergo follow-up procedures per the protocol. The study aims to evaluate safety and effectiveness of the two techniques in a real-world clinical setting. Enrollment requires candidates for ureteroscopy with laser lithotripsy who can comply with follow-up and provide informed consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Candidate for ureteroscopy with laser lithotripsy
* Be willing and able to return for and respond to all study-related follow up procedures
* Have been informed of the nature of the study and has provided informed consent using the IRB approved informed consent (ICF)

Exclusion Criteria:

* Untreated urinary tract infection at the time of the index procedure
* Significant comorbidities
* Bladder, ureteral or kidney abnormalities
* Pregnant individuals
* Unable to meet the treatment and follow up protocol requirements

Where it's running

• The University of Alabama at Birmingham
  Birmingham, Alabama, United States Recruiting
• University of Florida
  Gainesville, Florida, United States Recruiting
• Icahn School of Medicine at Mount Sinai
  New York, New York, United States Recruiting
• OhioHealth Research Institute
  Columbus, Ohio, United States Recruiting
• MidLantic Urology
  Bala-Cynwyd, Pennsylvania, United States Recruiting
• The University of Texas at Austin, Dell Medical School
  Austin, Texas, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing robotic and manual methods for treating kidney stones

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• Acupressure to Ease Pain During ESWL for Kidney Stones

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  Recruiting Medipol University · Istanbul · NCT07885696

• Audio consent with human voice or AI-voice added to written consent for ureteroscopy

  This study tests if listening to an audio version of the consent form, read by a real urologist or by an AI-cloned voice, helps adults in Turkey understand their ureteroscopy or RIRS consent better than the written form alone.

  Recruiting at 3 sites Aydin Adnan Menderes University · Aydin, Aydın and 2 other locations · NCT07859436

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.