Clinical trial Recruiting at 1 site Observational Ages 18 and up

Spinal versus general anesthesia for recovery after total knee replacement

Official title: Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia: A Retrospective Single-Center Observational Comparative Superiority Study

Run by University Hospital, Strasbourg, France · NCT07275983 · Data updated 2026-11-12

This will test whether spinal anesthesia or general anesthesia leads to better early postoperative recovery for adults who have had total knee replacement.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversity Hospital, Strasbourg, France
Academic / other
Locations1 site (Strasbourg)
StatusRecruiting
StartedMay 3, 2024
Main results expectedDecember 3, 2025
Study endsDecember 3, 2025
Registry record updatedDecember 10, 2025
Trial IDNCT07275983 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18 and older) who had a primary total knee replacement at CHU de Strasbourg between Jan 1, 2020 and Jun 30, 2023 and have a recorded QoR-15F score are the ideal candidates for inclusion.

Probably not a fit

Patients who had revision, emergency, bilateral, oncological, or septic knee surgeries, those treated outside the specified date range, or without QoR-15F data are unlikely to be included or to directly benefit from this analysis.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective observational comparison of postoperative recovery after total knee replacement using the QoR-15F recovery score. It includes adults (≥18 years) who underwent primary TKR at CHU de Strasbourg between January 1, 2020 and June 30, 2023 and had QoR-15F recorded. Patients who had revision, emergency, bilateral, oncological, or septic procedures, or who objected to reuse of their data, are excluded. The primary analysis compares QoR-15F scores between spinal anesthesia and general anesthesia groups.

Why it matters

Potential benefit: If one anesthesia type is associated with better QoR-15F scores, clinicians could favor that approach to improve early recovery after TKR.

How similar studies have gone: There are few or no prior studies that specifically compare postoperative functional recovery after TKR by anesthesia type using the QoR-15F, so this analysis is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female, 18 years of age or older (no upper age limit)
* Underwent total knee replacement surgery between January 1, 2020 and June 30, 2023
* Assessed using the QoR-15F score

Exclusion Criteria:

* Subject (and/or their legal representative, if applicable) who expressed their opposition to the reuse of their data for scientific research purposes.
* Revision, emergency, oncological, bilateral, or septic surgery

Where it's running

  • Service d'Anesthésiologie - Réanimation Chirurgicale - CHU de Strasbourg - France
    Strasbourg, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.