Spinal versus general anesthesia for recovery after total knee replacement
Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia: A Retrospective Single-Center Observational Comparative Superiority Study
This will test whether spinal anesthesia or general anesthesia leads to better early postoperative recovery for adults who have had total knee replacement.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT07275983 on ClinicalTrials.gov |
What this trial studies
This is a retrospective observational comparison of postoperative recovery after total knee replacement using the QoR-15F recovery score. It includes adults (≥18 years) who underwent primary TKR at CHU de Strasbourg between January 1, 2020 and June 30, 2023 and had QoR-15F recorded. Patients who had revision, emergency, bilateral, oncological, or septic procedures, or who objected to reuse of their data, are excluded. The primary analysis compares QoR-15F scores between spinal anesthesia and general anesthesia groups.
Who should consider this trial
Good fit: Adults (18 and older) who had a primary total knee replacement at CHU de Strasbourg between Jan 1, 2020 and Jun 30, 2023 and have a recorded QoR-15F score are the ideal candidates for inclusion.
Not a fit: Patients who had revision, emergency, bilateral, oncological, or septic knee surgeries, those treated outside the specified date range, or without QoR-15F data are unlikely to be included or to directly benefit from this analysis.
Why it matters
Potential benefit: If one anesthesia type is associated with better QoR-15F scores, clinicians could favor that approach to improve early recovery after TKR.
How similar studies have performed: There are few or no prior studies that specifically compare postoperative functional recovery after TKR by anesthesia type using the QoR-15F, so this analysis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female, 18 years of age or older (no upper age limit) * Underwent total knee replacement surgery between January 1, 2020 and June 30, 2023 * Assessed using the QoR-15F score Exclusion Criteria: * Subject (and/or their legal representative, if applicable) who expressed their opposition to the reuse of their data for scientific research purposes. * Revision, emergency, oncological, bilateral, or septic surgery
Where this trial is running
Strasbourg
- Service d'Anesthésiologie - Réanimation Chirurgicale - CHU de Strasbourg - France — Strasbourg, France (Recruiting)
Study contacts
- Study coordinator: Eric NOLL, MD, PhD
- Email: eric.noll@chru-strasbourg.fr
- Phone: 33 3 88 12 70 76
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.