Spinal (intrathecal) morphine versus bi-level erector spinae plane block for pain after living liver donation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two regional anesthesia techniques—intrathecal morphine (ITM) and a bi-level erector spinae plane block (ESPB)—for postoperative pain control in living liver donors. Participants who meet inclusion criteria will receive one of the two analgesic approaches around the time of donor hepatectomy. Outcomes will include postoperative pain scores, perioperative opioid consumption, and procedure-related adverse effects. The goal is to determine which technique provides better pain relief and fewer opioid-related problems to support faster recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-65 years
* American Society of Anesthesiologists (ASA) score I-II
* Body Mass Index (BMI) between 18-30 kg/m2

Exclusion Criteria:

* Patients under 18 and over 65 years of age
* ASA score III and above
* Patients with a history of bleeding diathesis
* BMI below 18 or above 30 kg/m2

Where it's running

• Ankara Etlik City Hospital
  Altındağ, Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Atakan Sezgi
• Email: kansezgi@gmail.com
• Phone: 00905323327000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Dexmedetomidine as add-on for refractory cancer pain in palliative care

  This study tests whether adding dexmedetomidine helps improve pain control for adults with cancer in palliative care whose pain remains high despite opioids.

  Recruiting St. Olavs Hospital · Drammen and 3 other locations · NCT07885475

• Two Ways to Help Pain After Breast Surgery: Education-Based Analgesia vs Standard Care

  This trial tests whether teaching patients about pain management and using a multimodal pain plan improves pain control and recovery after breast surgery compared with standard care.

  Recruiting University General Hospital of Heraklion · Heraklion, Crete · NCT07880223

• Virtual Reality Therapy to Improve Arthroplasty Outcomes

  This pilot test checks whether using virtual reality during the perioperative period helps knee or hip replacement patients feel better about their care and recover more easily.

  Recruiting NHS Highland Research, Development and Innovation Organisation · Inverness, Highlands · NCT07872670

• Suzetrigine for pain relief after knee replacement

  This trial tests whether suzetrigine can reduce opioid use after a total knee replacement compared with placebo.

  Recruiting Phase 3 Hospital for Special Surgery, New York · New York, New York · NCT07864896

• Analgesic effects of adding BiFeS block to adductor canal block after ACL reconstruction

  This study tests whether adding a BiFeS block to the standard adductor canal block provides better pain relief after ACL reconstruction.

  Recruiting Ankara Etlik City Hospital · Ankara · NCT07859397

• Tegileridine for pain after bariatric surgery

  This phase 3 trial tests tegileridine vs standard opioid medicine to see if it provides good pain relief after bariatric surgery while considering sleep apnea status.

  Recruiting Phase 3 The First Hospital of Jilin University · Changchun, Jilin · NCT07844512

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.