Spectral CT during embolization and ablation for liver and kidney tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot will collect intra-procedural spectral CT images using Canon Medical's 4D CT system during mapping arteriography before trans-arterial radioembolization (TARE) and during tumor ablation. The study will record feasibility of image acquisition, image quality, and procedural utility such as shunt fraction estimation, lesion identification, T:N dose ratio prediction, and dose distribution. It will also explore spectral CT-derived effective atomic number maps to detect physiologic tissue changes during ablation in both ex vivo models and clinical ablation procedures. Procedures will be performed at VA Palo Alto Healthcare System in collaboration with Canon Medical Systems without altering standard clinical workflow.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Age \> or = 18 years
2. Tumor in an area without prior surgical or ablative therapy
3. At least 1 tumor greater than 1.5 cm in greatest diameter

Exclusion criteria:

1. Not eligible for indicated procedure.
2. BMI \> 35
3. Prior surgery.

Where it's running

• VA Palo Alto Healthcare System
  Palo Alto, California, United States Recruiting

Study contacts

• Principal investigator: Sirish Kishore, MD — VA Palo Alto Health Care System
• Study coordinator: Sirish Kishore, MD
• Email: sirish.kishore@va.gov
• Phone: 650-493-5000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.